Pathophysiology of Peyronie's disease

被引：55
作者：
Moreland, RB
Nehra, A
机构：
[1] Mayo Clin & Mayo Fdn, Dept Urol, Rochester, MN 55905 USA
[2] Boston Univ, Sch Med, Dept Urol & Physiol, Boston, MA 02215 USA
来源：
INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH | 2002年 / 14卷 / 05期
关键词：
Peyronie's; genetics; TGF-beta(1);
D O I：
10.1038/sj.ijir.3900875
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
Peyronie's disease is an inflammatory condition characterized by the formation of fibrous, noncompliant nodules in the tunica albuginea which can impede tunical expansion during penile erection, leading to deformity and bending. While the cause of this disease is thought to be due to microvascular trauma and abnormal wound healing, other hypotheses include genetic predisposition. In this review the pathophysiology of Peyronie's disease is discussed as well as current hypothese regarding its origin.
引用
收藏
页码：406 / 410
页数：5
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