Aziridine-modified amino alcohols as efficient modular catalysts for highly enantioselective alkenylzinc additions to aldehydes

被引：11

作者：

Braga, Antonio L. ^{[1
]}

Paixao, Marcio W.

Westermann, Bernhard

Schneider, Paulo H.

Wessjohann, Ludger A.

机构：

[1] Univ Fed Santa Maria, Dept Quim, BR-97105900 Santa Maria, RS, Brazil

[2] Leibniz Inst Plant Biochem, D-06120 Halle, Saale, Germany

[3] Univ Fed Rio Grande do Sul, Inst Quim, Porto Alegre, RS, Brazil

来源：

SYNLETT | 2007年 / 06期

关键词：

asymmetric synthesis; allylic alcohols; vinyl addition; alkenylzinc; aziridino alcohols;

D O I：

10.1055/s-2007-973879

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

N-Tritylaziridino alcohols have been easily synthesized in a straightforward synthetic route from an inexpensive and easily available chiral pool. They were used in the enantioselective alkenylzinc additions to aldehydes furnishing the products in excellent yields and stereosetectivities up to 97%.

引用

页码：917 / 920

页数：4

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