GHKL, an emergent ATPase/kinase superfamily

被引：649

作者：

Dutta, R ^{[1
]}

Inouye, M ^{[1
]}

机构：

[1] Robert Wood Johnson Med Sch, Dept Biochem, Piscataway, NJ 08854 USA

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 2000年 / 25卷 / 01期

关键词：

D O I：

10.1016/S0968-0004(99)01503-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

An interesting recent development is the recognition of a novel ATP-binding superfamily that includes diverse protein families such as DNA topoisomerase II, molecular chaperones Hsp90, DNA-mismatch-repair enzymes MutL and histidine kinases. The most singular unifying feature of this superfamily is the unconventional Bergerat ATP-binding fold. The far-reaching significance of this commonality is still in the process of being explored.

引用

页码：24 / 28

页数：5

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