Evolutionary history of the calcitonin gene-related peptide family in vertebrates revealed by comparative genomic analyses

被引：59

作者：

Ogoshi, Maho ^{[1
]}

Inoue, Koji

Naruse, Kiyoshi

Takei, Yoshio

机构：

[1] Univ Tokyo, Ocean Res Inst, Tokyo 1648639, Japan

[2] Univ Tokyo, Grad Sch Sci, Dept Biol Sci, Tokyo 1130033, Japan

来源：

PEPTIDES | 2006年 / 27卷 / 12期

基金：

日本学术振兴会;

关键词：

CGRP; amylin; adrenomedullin; linkage analyses; molecular evolution;

D O I：

10.1016/j.peptides.2006.09.011

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The calcitonin gene-related peptide (CGRP) family is composed of CGRP, amylin and adrenomedullin (AM) in mammals. In teleost fish, AM forms an independent subfamily of five members (AM1-5), which inspired us to trace the evolutionary history of the CGRP family throughout vertebrates by comparative genomic approach. Linkage mapping and synteny analyses of the CGRP family genes in medaka, Oryzias latipes, revealed that AM1/CGRP, AM2/amylin, and AM5 genes were located on respective proto-chromosomes before the divergence of teleost lineage. In teleost fish, additional whole genome duplication generated AM1/4, CGRP1/2, AM2/3, but one of the duplicated amylin and AM5 genes was silenced. In mammals, the amylin or AM2 gene was translocated to different chromosomes, while the CGRP gene was multiplied in tandem to generate CGRP-alpha,beta, and recently identified calcitonin receptor-stimulating peptide genes. Based on these data, we identified a novel AM5 gene in several mammalian species as we previously did for AM2. (c) 2006 Elsevier Inc. All rights reserved.

引用

页码：3154 / 3164

页数：11

共 34 条

[1] EXPRESSION BRAIN OF A MESSENGER-RNA ENCODING A NOVEL NEUROPEPTIDE HOMOLOGOUS TO CALCITONIN GENE-RELATED PEPTIDE [J].

AMARA, SG ;

ARRIZA, JL ;

LEFF, SE ;

SWANSON, LW ;

EVANS, RM ;

ROSENFELD, MG .

SCIENCE, 1985, 229 (4718) :1094-1097

[2]

[Anonymous], 1997, INTEGRATED BOOK BIOL

[3] Vascular actions of calcitonin gene-related peptide and adrenomedullin [J].

Brain, SD ;

Grant, AD .

PHYSIOLOGICAL REVIEWS, 2004, 84 (03) :903-934

[4] Calcitonin:: characterisation and expression in a teleost fish, Fugu rubripes [J].

Clark, MS ;

Bendell, L ;

Power, DM ;

Warner, S ;

Elgar, G ;

Ingleton, PM .

JOURNAL OF MOLECULAR ENDOCRINOLOGY, 2002, 28 (02) :111-123

[5] HIGH-RESOLUTION CHROMOSOMAL LOCALIZATION OF THE HUMAN CALCITONIN CGRP/IAPP GENE FAMILY MEMBERS [J].

HOOVERS, JMN ;

REDEKER, E ;

SPELEMAN, F ;

HOPPENER, JWM ;

BHOLA, S ;

BLIEK, J ;

VANROY, N ;

LESCHOT, NJ ;

WESTERVELD, A ;

MANNENS, M .

GENOMICS, 1993, 15 (03) :525-529

[6]

Höppener JWM, 2000, NEW ENGL J MED, V343, P411

[7] Four functionally distinct C-type natriuretic peptides found in fish reveal evolutionary history of the natriuretic peptide system [J].

Inoue, K ;

Naruse, K ;

Yamagami, S ;

Mitani, H ;

Suzuki, N ;

Takei, Y .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (17) :10079-10084

[8] C-type natriuretic peptide of rainbow trout (Oncorhynchus mykiss):: primary structure and vasorelaxant activities [J].

Inoue, K ;

Russell, MJ ;

Olson, KR ;

Takei, Y .

GENERAL AND COMPARATIVE ENDOCRINOLOGY, 2003, 130 (02) :185-192

[9] Diuretic and natriuretic action of adrenomedullin administered intracerebroventricularly in conscious rats [J].

Israel, A ;

Diaz, E .

REGULATORY PEPTIDES, 2000, 89 (1-3) :13-18

[10] Genome duplication in the teleost fish Tetraodon nigroviridis reveals the early vertebrate proto-karyotype [J].

Jaillon, O ;

Aury, JM ;

Brunet, F ;

Petit, JL ;

Stange-Thomann, N ;

Mauceli, E ;

Bouneau, L ;

Fischer, C ;

Ozouf-Costaz, C ;

Bernot, A ;

Nicaud, S ;

Jaffe, D ;

Fisher, S ;

Lutfalla, G ;

Dossat, C ;

Segurens, B ;

Dasilva, C ;

Salanoubat, M ;

Levy, M ;

Boudet, N ;

Castellano, S ;

Anthouard, R ;

Jubin, C ;

Castelli, V ;

Katinka, M ;

Vacherie, B ;

Biémont, C ;

Skalli, Z ;

Cattolico, L ;

Poulain, J ;

de Berardinis, V ;

Cruaud, C ;

Duprat, S ;

Brottier, P ;

Coutanceau, JP ;

Gouzy, J ;

Parra, G ;

Lardier, G ;

Chapple, C ;

McKernan, KJ ;

McEwan, P ;

Bosak, S ;

Kellis, M ;

Volff, JN ;

Guigó, R ;

Zody, MC ;

Mesirov, J ;

Lindblad-Toh, K ;

Birren, B ;

Nusbaum, C .

NATURE, 2004, 431 (7011) :946-957

← 1 2 3 4 →