Microbiome engineering: Current applications and its future

被引：110
作者：
Foo, Jee Loon [1 ,2 ]
Ling, Hua [1 ,2 ]
Lee, Yung Seng [2 ,3 ]
Chang, Matthew Wook [1 ,2 ]
机构：
[1] Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Biochem, 8 Med Dr, Singapore 117597, Singapore
[2] Natl Univ Singapore, Inst Life Sci, NUS Synthet Biol Clin & Technol Innovat SynCTI, Singapore, Singapore
[3] Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Paediat, Singapore 117548, Singapore
来源：
BIOTECHNOLOGY JOURNAL | 2017年 / 12卷 / 03期
基金：
英国医学研究理事会;
关键词：
Agricultural productivity; Human health; Microbiome engineering; Microbiota; GUT MICROBIOTA; CLOSTRIDIUM-DIFFICILE; SOIL MICROBIOME; FECAL TRANSPLANT; IMPROVE PLANT; HEALTH; DIVERSITY; RESPONSES; OLIGOSACCHARIDES; AGRICULTURE;
D O I：
10.1002/biot.201600099
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Microbiomes exist in all ecosystems and are composed of diverse microbial communities. Perturbation to microbiomes brings about undesirable phenotypes in the hosts, resulting in diseases and disorders, and disturbs the balance of the associated ecosystems. Engineering of microbiomes can be used to modify structures of the microbiota and restore ecological balance. Consequently, microbiome engineering has been employed for improving human health and agricultural productivity. The importance and current applications of microbiome engineering, particularly in humans, animals, plants and soil is reviewed. Furthermore, we explore the challenges in engineering microbiome and the future of this field, thus providing perspectives and outlook of microbiome engineering.
引用
收藏
页数：9
相关论文
共 63 条
[1]   Microbial Hub Taxa Link Host and Abiotic Factors to Plant Microbiome Variation [J].
Agler, Matthew T. ;
Ruhe, Jonas ;
Kroll, Samuel ;
Morhenn, Constanze ;
Kim, Sang-Tae ;
Weigel, Detlef ;
Kemen, Eric M. .
PLOS BIOLOGY, 2016, 14 (01)
[2]   Engineering Modular Viral Scaffolds for Targeted Bacterial Population Editing [J].
Ando, Hiroki ;
Lemire, Sebastien ;
Pires, Diana P. ;
Lu, Timothy K. .
CELL SYSTEMS, 2015, 1 (03) :187-196
[3]   Manipulating the soil microbiome to increase soil health and plant fertility [J].
Chaparro, Jacqueline M. ;
Sheflin, Amy M. ;
Manter, Daniel K. ;
Vivanco, Jorge M. .
BIOLOGY AND FERTILITY OF SOILS, 2012, 48 (05) :489-499
[4]   Prebiotic Potential of a Maize-Based Soluble Fibre and Impact of Dose on the Human Gut Microbiota [J].
Costabile, Adele ;
Deaville, Eddie R. ;
Morales, Agustin Martin ;
Gibson, Glenn R. .
PLOS ONE, 2016, 11 (01)
[5]   Effects of Xylo-Oligosaccharides on Broiler Chicken Performance and Microbiota [J].
De Maesschalck, C. ;
Eeckhaut, V. ;
Maertens, L. ;
De Lange, L. ;
Marchal, L. ;
Nezer, C. ;
De Baere, S. ;
Croubels, S. ;
Daube, G. ;
Dewulf, J. ;
Haesebrouck, F. ;
Ducatelle, R. ;
Taminau, B. ;
Van Immerseel, F. .
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2015, 81 (17) :5880-5888
[6]   The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism [J].
den Besten, Gijs ;
van Eunen, Karen ;
Groen, Albert K. ;
Venema, Koen ;
Reijngoud, Dirk-Jan ;
Bakker, Barbara M. .
JOURNAL OF LIPID RESEARCH, 2013, 54 (09) :2325-2340
[7]   Engineered bacterial communication prevents Vibrio cholerae virulence in an infant mouse model [J].
Duan, Faping ;
March, John C. .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2010, 107 (25) :11260-11264
[8]   Structure, variation, and assembly of the root-associated microbiomes of rice [J].
Edwards, Joseph ;
Johnson, Cameron ;
Santos-Medellin, Christian ;
Lurie, Eugene ;
Podishetty, Natraj Kumar ;
Bhatnagar, Srijak ;
Eisen, Jonathan A. ;
Sundaresan, Venkatesan .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2015, 112 (08) :E911-E920
[9]   Should the Human Microbiome Be Considered When Developing Vaccines? [J].
Ferreira, Rosana B. R. ;
Antunes, L. Caetano M. ;
Finlay, B. Brett .
PLOS PATHOGENS, 2010, 6 (11)
[10]  
Frampton R.A., 2012, INT J MICROBIOL, V2012, DOI [10.1155/2012/326452, DOI 10.1155/2012/326452]
1234567