Asymmetric synthesis of densely functionalized pyrazolidines and 1,3-diamines

被引：0
作者：
Chauveau, A
Martens, T
Bonin, M
Micouin, L
Husson, HP
机构：
[1] CNRS, UMR 8638, Chim Therapeut Lab, F-75270 Paris 06, France
[2] Univ Paris 05, Fac Sci Pharmaceut & Biol, F-75270 Paris, France
来源：
SYNTHESIS-STUTTGART | 2002年 / 13期
关键词：
asymmetric synthesis; cycloadditions; ylides; reductions; chemoselectivity;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A versatile and straightforward access to polysubstituted 1,3-diamines with good control of relative and absolute configurations is described. The key steps involve a diastereoselective 1,3-dipolar cycloaddition of a chiral non-racemic azomethine imine ylide and a chemoselective electroreduction of densely functionalized pyrazolidines intermediates.
引用
收藏
页码：1885 / 1890
页数：6
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