Haemophilia imaging: a review

被引:29
作者
Maclachlan, Jody [1 ]
Gough-Palmer, Antony [1 ]
Hargunani, Rikin [1 ]
Farrant, Joanna [1 ]
Holloway, Brian [1 ]
机构
[1] Royal Free Hosp, London NW3 2QG, England
关键词
Haemophilia; Imaging; Musculoskeletal; HEPATITIS-C; INHIBITOR TREATMENT; LIVER-DISEASE; MRI FINDINGS; FACTOR-VIII; X-RAY; MANAGEMENT; CHILDREN; ARTHROPATHY; JOINTS;
D O I
10.1007/s00256-008-0586-5
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
Haemophilia disorders are characterised by a blood coagulation anomaly leading to prolonged and excessive bleeding. Imaging provides an essential role in the investigation of both the musculoskeletal and the non-musculoskeletal complications of haemophilia. Our institution is home to a large tertiary referral centre for haemophilia treatment. Using our broad experience, we present a multi-modality pictorial review of the musculoskeletal manifestations of haemophilia, including haemophilic arthropathy, intra-muscular haemorrhage and haemophilic pseudotumour. The main imaging features of haemophilic arthropathy are described, including synovial hypertrophy, haemosiderin deposition, sub-chondral cyst formation and loss of joint space.
引用
收藏
页码:949 / 957
页数:9
相关论文
共 35 条
[1]   Inhibitor treatment in haemophillas A and B: Summary statement for the 2006 International Consensus Conference [J].
Berntorp, E. ;
Shapiro, A. ;
Astermark, J. ;
Blanchette, V. S. ;
Collins, P. W. ;
Dimichele, D. ;
Escuriola, C. ;
Hay, C. R. M. ;
Hoots, W. K. ;
Leissinger, C. A. ;
Negrier, C. ;
Oldenburg, J. ;
Peerlinck, K. ;
Reding, M. T. ;
Hart, C. .
HAEMOPHILIA, 2006, 12 :1-7
[2]   MR APPEARANCE OF HEMORRHAGE IN THE BRAIN [J].
BRADLEY, WG .
RADIOLOGY, 1993, 189 (01) :15-26
[3]   The magnetic resonance imaging of musculoskeletal hemorrhage [J].
Bush, CH .
SKELETAL RADIOLOGY, 2000, 29 (01) :1-9
[4]   A population based, unselected, consecutive cohort of patients with acquired haemophilia A [J].
Collins, P ;
Macartney, N ;
Davies, R ;
Lees, S ;
Giddings, J ;
Majer, R .
BRITISH JOURNAL OF HAEMATOLOGY, 2004, 124 (01) :86-90
[5]   Inhibitor treatment in haemophilias A and B: inhibitor diagnosis [J].
Dimichele, D. M. .
HAEMOPHILIA, 2006, 12 :37-41
[6]  
EYSTER ME, 1993, J ACQ IMMUN DEF SYND, V6, P602
[7]   The effects of postponing prophylactic treatment on long-term outcome in patients with severe hemophilia [J].
Fischer, K ;
van der Bom, JG ;
Mauser-Bunschoten, EP ;
Roosendaal, G ;
Prejs, R ;
de Kleijn, P ;
Grobbee, DE ;
van den Berg, M .
BLOOD, 2002, 99 (07) :2337-2341
[8]   Acquired hemophilia A: A concise review [J].
Franchini, M ;
Gandini, G ;
Di Paolantonio, T ;
Mariani, G .
AMERICAN JOURNAL OF HEMATOLOGY, 2005, 80 (01) :55-63
[9]  
Gomori J M, 1988, Radiographics, V8, P427
[10]   INTRACRANIAL HEMATOMAS - IMAGING BY HIGH-FIELD MR [J].
GOMORI, JM ;
GROSSMAN, RI ;
GOLDBERG, HI ;
ZIMMERMAN, RA ;
BILANIUK, LT .
RADIOLOGY, 1985, 157 (01) :87-93