Palladium-Catalyzed C(sp2)-H Acetoxylation via Electrochemical Oxidation

被引：118

作者：

Li, Yi-Qian ^{[1
,2
]}

Yang, Q-Liang ^{[2
]}

Fang, Ping ^{[2
]}

Mei, Tian-Sheng ^{[2
]}

Zhang, Dayong ^{[1
]}

机构：

[1] China Pharmaceut Univ, Inst Pharmaceut Sci, Nanjing, Jiangsu, Peoples R China

[2] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, 345 Lingling Rd, Shanghai 200032, Peoples R China

来源：

ORGANIC LETTERS | 2017年 / 19卷 / 11期

关键词：

C-H ACETOXYLATION; FORMING REDUCTIVE ELIMINATION; DIRECTING-GROUP; UNACTIVATED C(SP(3))-H; FUNCTIONALIZATION; OXYGENATION; BONDS; ACID; HYDROXYLATION; COMPLEXES;

D O I：

10.1021/acs.orglett.7b01138

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Palladium-catalyzed arene C(sp2)H acetoxylation has emerged as a powerful tool to construct a carbonoxygen (CO) bond. However, the requirement of stoichiometric chemical oxidants for this transformation possesses a significant disadvantage. To solve this fundamental problem, we now report an anodic oxidation strategy to achieve arene C(sp(2))H acetoxylation.

引用

页码：2905 / 2908

页数：4

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