The enantioselective conversion of three-membered ring sulfoxides (episulfoxides) into alkenyl sulfoxides using chiral lithium amide bases

被引：0

作者：

Blake, AJ ^{[1
]}

Westaway, SM ^{[1
]}

Simpkins, NS ^{[1
]}

机构：

[1] UNIV NOTTINGHAM,DEPT CHEM,NOTTINGHAM NG7 2RD,ENGLAND

来源：

SYNLETT | 1997年 / 08期

关键词：

episulfoxide; alkenyl sulfoxide; chiral lithium amide base;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel type of chiral lithium amide base reaction, involving the rearrangement of certain types of symmetrical ring-fused episulfoxides, gives alkenyl sulfoxide products in up to 88% ee. The structure of one product, including its absolute stereochemistry, was determined by X-ray crystallography, following oxidation of the sulfoxide to the corresponding alkenyl sulfone.

引用

页码：919 / &

页数：3