Barium manganate in microwave-assisted oxidation reactions: synthesis of lactones by oxidative cyclization of diols

被引：35

作者：

Bagley, Mark C. ^{[1
]}

Lin, Zhifan ^{[1
]}

Phillips, David J. ^{[1
]}

Graham, Andrew E. ^{[1
]}

机构：

[1] Cardiff Univ, Sch Chem, Cardiff CF10 3AT, S Glam, Wales

来源：

TETRAHEDRON LETTERS | 2009年 / 50卷 / 49期

基金：

英国工程与自然科学研究理事会;

关键词：

WERNER-SYNDROME CELLS; HIGHLY EFFICIENT SYNTHESIS; SELECTIVE MONOACYLATION; SILICA-GEL; HEATING ELEMENTS; ALCOHOLS; DEHYDROGENATION; DIOXIDE; DESYMMETRIZATION; ELECTROOXIDATION;

D O I：

10.1016/j.tetlet.2009.09.117

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Microwave irradiation of a range of diols at 150 degrees C in acetonitrile in the presence of three equivalents of barium manganate facilitates a novel tandem oxidation/heterocyclocondensation to give the corresponding lactone, including both small and medium ring lactones, in only one hour and in high yield without the need for chromatographic purification. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：6823 / 6825

页数：3

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