MicroRNAs for Diagnosis and Treatment of Colorectal Cancer

被引:7
|
作者
Mei, Haitao [1 ]
Wen, Yugang [1 ]
机构
[1] Shanghai Jiao Tong Univ, Sch Med, Shanghai Gen Hosp, Dept Gen Surg, Shanghai, Peoples R China
关键词
CRC; diagnosis and treatment; liquid biopsy; miRNA; combined-biomarkers testing; tumorigenesis; TARGETED PROTEOMICS; BIOMARKERS; EXPRESSION; PROGNOSIS; CETUXIMAB; DELIVERY; GENES; CELLS; MIR-143/145; BIOGENESIS;
D O I
10.2174/1871530320999200818134339
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Colorectal cancer (CRC) is the third most common cancer worldwide, with high morbidity and mortality rates. The diagnosis and treatment of CRC have the most significant value for disease-free survival. Early diagnosis and early surgical resection are generally considered to be the most effective ways to reduce CRC mortality. In the past few years, many researchers have focused on the role of microRNAs in different tumors, making the functions of microRNAs gradually clear. The present study reviews the role of microRNAs in the diagnosis and treatment of colorectal cancer. Compared with the usual diagnosis methods and biomarker, circulating microRNAs can be promising new effective biomarkers for CRC diagnosis and treatment.
引用
收藏
页码:47 / 55
页数:9
相关论文
共 50 条
  • [21] Current diagnosis and treatment - Diagnosis of hereditary colorectal cancer
    Caspari, R
    Jungck, M
    Lamberti, C
    Schmidt-Wolf, IGH
    Friedl, W
    Propping, P
    DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT, 2000, 125 (06) : 153 - 158
  • [22] CIRCULATING microRNAs IN COLORECTAL CANCER
    Nugent, M.
    Kheirelseid, E. A. H.
    Heneghan, H. M.
    Chang, K. H.
    Miller, N.
    Kerin, M. J.
    IRISH JOURNAL OF MEDICAL SCIENCE, 2010, 179 : S345 - S345
  • [23] MicroRNAs in colorectal cancer metastasis
    de Krijger, Inge
    Mekenkamp, Leonie J. M.
    Punt, Cornelis J. A.
    Nagtegaal, Iris D.
    JOURNAL OF PATHOLOGY, 2011, 224 (04): : 438 - 447
  • [24] The role of microRNAs in colorectal cancer
    Liu, Mao
    Chen, Huiping
    JOURNAL OF GENETICS AND GENOMICS, 2010, 37 (06) : 347 - 358
  • [25] MicroRNAs and Inflammation in Colorectal Cancer
    Josse, Claire
    Bours, Vincent
    NON-CODING RNAS IN COLORECTAL CANCER, 2016, 937 : 53 - 69
  • [26] Circulating micrornas in colorectal cancer
    Nugent, M.
    Miller, N.
    Kerin, M. J.
    BRITISH JOURNAL OF SURGERY, 2010, 97 : 15 - 15
  • [27] MicroRNAs and Apoptosis in Colorectal Cancer
    Wang, Hsiuying
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 21 (15) : 1 - 15
  • [28] The impact of microRNAs on colorectal cancer
    Faber, Claudius
    Kirchner, Thomas
    Hlubek, Falk
    VIRCHOWS ARCHIV, 2009, 454 (04) : 359 - 367
  • [29] MicroRNAs as Biomarkers in Colorectal Cancer
    Masuda, Takaaki
    Hayashi, Naoki
    Kuroda, Yosuke
    Ito, Shuhei
    Eguchi, Hidetoshi
    Mimori, Koshi
    CANCERS, 2017, 9 (09):
  • [30] The Role of MicroRNAs in Colorectal Cancer
    Schetter, Aaron J.
    Okayama, Hirokazu
    Harris, Curtis C.
    CANCER JOURNAL, 2012, 18 (03): : 244 - 252