MicroRNAs for Diagnosis and Treatment of Colorectal Cancer

被引:7
|
作者
Mei, Haitao [1 ]
Wen, Yugang [1 ]
机构
[1] Shanghai Jiao Tong Univ, Sch Med, Shanghai Gen Hosp, Dept Gen Surg, Shanghai, Peoples R China
关键词
CRC; diagnosis and treatment; liquid biopsy; miRNA; combined-biomarkers testing; tumorigenesis; TARGETED PROTEOMICS; BIOMARKERS; EXPRESSION; PROGNOSIS; CETUXIMAB; DELIVERY; GENES; CELLS; MIR-143/145; BIOGENESIS;
D O I
10.2174/1871530320999200818134339
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Colorectal cancer (CRC) is the third most common cancer worldwide, with high morbidity and mortality rates. The diagnosis and treatment of CRC have the most significant value for disease-free survival. Early diagnosis and early surgical resection are generally considered to be the most effective ways to reduce CRC mortality. In the past few years, many researchers have focused on the role of microRNAs in different tumors, making the functions of microRNAs gradually clear. The present study reviews the role of microRNAs in the diagnosis and treatment of colorectal cancer. Compared with the usual diagnosis methods and biomarker, circulating microRNAs can be promising new effective biomarkers for CRC diagnosis and treatment.
引用
收藏
页码:47 / 55
页数:9
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