Assessing the Impact of COVID-19 on Antimicrobial Stewardship Activities/Programs in the United Kingdom

被引:61
作者
Ashiru-Oredope, Diane [1 ]
Kerr, Frances [2 ]
Hughes, Stephen [1 ]
Urch, Jonathan [1 ]
Lanzman, Marisa [1 ]
Yau, Ting [1 ]
Cockburn, Alison [2 ]
Patel, Rakhee [1 ]
Sheikh, Adel [1 ]
Gormley, Cairine [3 ]
Chavda, Aneeka [1 ]
Vaghela, Tejal [1 ]
Phillips, Ceri [4 ]
Reid, Nicholas [4 ]
Brady, Aaron [3 ]
机构
[1] United Kingdom Clin Pharm Assoc UKCPA, Pharm Infect Network PIN, Leicester LE2 5BB, Leics, England
[2] Assoc Scottish Antimicrobial Pharmacists, Airdrie ML6 8ES, Scotland
[3] Northern Ireland Reg Antimicrobial Pharmacists Ne, Belfast BT2 8BS, Antrim, North Ireland
[4] All Wales Antimicrobial Pharmacists Grp, Cardiff CF10 4BZ, Wales
来源
ANTIBIOTICS-BASEL | 2021年 / 10卷 / 02期
关键词
COVID-19; antimicrobial stewardship (AMS); antimicrobial resistance (AMR); coronavirus; SARS-CoV-2;
D O I
10.3390/antibiotics10020110
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Since first identified in late 2019, the acute respiratory syndrome coronavirus (SARS-CoV2) and the resulting coronavirus disease (COVID-19) pandemic has overwhelmed healthcare systems worldwide, often diverting key resources in a bid to meet unprecedented challenges. To measure its impact on national antimicrobial stewardship (AMS) activities, a questionnaire was designed and disseminated to antimicrobialstewardship leads in the United Kingdom (UK). Most respondents reported a reduction in AMS activity with 64% (61/95) reporting that COVID-19 had a negative impact on routine AMS activities. Activities reported to have been negatively affected by the pandemic include audit, quality improvement initiatives, education, AMS meetings, and multidisciplinary working including ward rounds. However, positive outcomes were also identified, with technology being increasingly used as a tool to facilitate stewardship, e.g., virtual meetings and ward rounds and increased the acceptance of using procalcitonin tests to distinguish between viral and bacterial infections. The COVID-19 pandemic has had a significant impact on the AMS activities undertaken across the UK. The long-term impact of the reduced AMS activities on incidence of AMR are not yet known. The legacy of innovation, use of technology, and increased collaboration from the pandemic could strengthen AMS in the post-pandemic era and presents opportunities for further development of AMS.
引用
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页码:1 / 13
页数:13
相关论文
共 32 条
[1]   Macrolides in critically ill patients with Middle East Respiratory Syndrome [J].
Arabi, Yaseen M. ;
Deeb, Ahmad M. ;
Al-Hameed, Fahad ;
Mandourah, Yasser ;
Almekhlafi, Ghaleb A. ;
Sindi, Anees A. ;
Al-Omari, Awad ;
Shalhoub, Sarah ;
Mady, Ahmed ;
Alraddadi, Basem ;
Almotairi, Abdullah ;
Al Khatib, Kasim ;
Abdulmomen, Ahmed ;
Qushmaq, Ismael ;
Solaiman, Othman ;
Al-Aithan, Abdulsalam M. ;
Al-Raddadi, Rajaa ;
Ragab, Ahmad ;
Al Harthy, Abdulrahman ;
Kharaba, Ayman ;
Jose, Jesna ;
Dabbagh, Tarek ;
Fowler, Robert A. ;
Balkhy, Hanan H. ;
Merson, Laura ;
Hayden, Frederick G. .
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 2019, 81 :184-190
[2]   Treatment with hydroxychloroquine, azithromycin, and combination in patients hospitalized with COVID-19 [J].
Arshad, Samia ;
Kilgore, Paul ;
Chaudhry, Zohra S. ;
Jacobsen, Gordon ;
Wang, Dee Dee ;
Huitsing, Kylie ;
Brar, Indira ;
Alangaden, George J. ;
Ramesh, Mayur S. ;
McKinnon, John E. ;
O'Neill, William ;
Zervos, Marcus .
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 2020, 97 :396-403
[3]  
Cavalcanti AB, 2020, NEW ENGL J MED, V383, P2041, DOI [10.1056/NEJMoa2019014, 10.1056/NEJMx200021]
[4]   Co-infections: potentially lethal and unexplored in COVID-19 [J].
Cox, Michael J. ;
Loman, Nicholas ;
Bogaert, Debby ;
O'Grady, Justin .
LANCET MICROBE, 2020, 1 (01) :E11-E11
[5]  
Cytlel Cytlel, GLOB COR COVID 19 CL
[6]  
Department of Health and Social Care, DRUG SHORT UPD SUPPL
[7]   Clinical and microbiological effect of a combination of hydroxychloroquine and azithromycin in 80 COVID-19 patients with at least a six-day follow up: A pilot observational study [J].
Gautret, Philippe ;
Lagier, Jean-Christophe ;
Parola, Philippe ;
Van Thuan Hoang ;
Meddeb, Line ;
Sevestre, Jacques ;
Mailhe, Morgane ;
Doudier, Barbara ;
Aubry, Camille ;
Amrane, Sophie ;
Seng, Piseth ;
Hocquart, Marie ;
Eldin, Carole ;
Finance, Julie ;
Vieira, Vera Esteves ;
Tissot-Dupont, Herve Tissot ;
Honore, Stephane ;
Stein, Andreas ;
Million, Matthieu ;
Colson, Philippe ;
La Scola, Bernard ;
Veit, Veronique ;
Jacquier, Alexis ;
Deharo, Jean-Claude ;
Drancourt, Michel ;
Fournier, Pierre Edouard ;
Rolain, Jean-Marc ;
Brouqui, Philippe ;
Raoult, Didier .
TRAVEL MEDICINE AND INFECTIOUS DISEASE, 2020, 34
[8]   Global contributions of pharmacists during the COVID-19 pandemic [J].
Goff, Debra A. A. ;
Ashiru-Oredope, Diane ;
Cairns, Kelly A. A. ;
Eljaaly, Khalid ;
Gauthier, Timothy P. P. ;
Langford, Bradley J. J. ;
Mahmoud, Sara Fouad ;
Messina, Angeliki P. P. ;
Michael, Ubaka Chukwuemeka ;
Saad, Therese ;
Schellack, Natalie .
JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, 2020, 3 (08) :1480-1492
[9]   Bacterial and fungal coinfection among hospitalized patients with COVID-19: a retrospective cohort study in a UK secondary-care setting [J].
Hughes, S. ;
Troise, O. ;
Donaldson, H. ;
Mughal, N. ;
Moore, L. S. P. .
CLINICAL MICROBIOLOGY AND INFECTION, 2020, 26 (10) :1395-1399
[10]   COVID-19: don't neglect antimicrobial stewardship principles! [J].
Huttner, B. D. ;
Catho, G. ;
Pano-Pardo, J. R. ;
Pulcini, C. ;
Schouten, J. .
CLINICAL MICROBIOLOGY AND INFECTION, 2020, 26 (07) :808-810