Treatment of chronic recurrent multifocal osteomyelitis with interferon gamma

被引：36

作者：

Gallagher, KT ^{[1
]}

Roberts, RL ^{[1
]}

MacFarlane, JA ^{[1
]}

Stiehm, ER ^{[1
]}

机构：

[1] UNIV CALIF LOS ANGELES, SCH MED, DIV IMMUNOL ALLERGY RHEUMATOL, DEPT PEDIAT, LOS ANGELES, CA 90095 USA

来源：

JOURNAL OF PEDIATRICS | 1997年 / 131卷 / 03期

关键词：

D O I：

10.1016/S0022-3476(97)80081-9

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Chronic recurrent multifocal osteomyelitis is characterized by recurrent episodes of painful swollen lesions of the bone and overlying skin with radiographic changes and an elevated sedimentation rate. It resembles infectious osteomyelitis but with negative findings on bacterial culture and no response to antibiotics. We treated a 13-year-old girl with interferon gamma for 3 months. She had 11 episodes of chronic recurrent multifocal osteomyelitis in 2 1/2 years before therapy and has had none in the 15 months since therapy, an outcome suggesting a favorable therapeutic response.

引用

页码：470 / 472

页数：3

共 20 条

[1] EFFECTIVE TREATMENT WITH INTERFERON-ALPHA IN CHRONIC RECURRENT MULTIFOCAL OSTEOMYELITIS [J].