Work-Related Asthma

被引：18
作者：
Jolly, Athena T.
Klees, Julia E.
Pacheco, Karin A.
Guidotti, Tee L.
Kipen, Howard M.
Biggs, Jeremy J.
Hyman, Mark H.
Bohnker, Bruce K.
Thiese, Matthew S.
Hegmann, Kurt T.
Harber, Philip
机构：
[1] University of Utah Rocky Mountain, Center for Occupational and Environmental Health, 391 Chipeta Way, Salt Lake City, 84108-1294, UT
来源：
JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE | 2015年 / 57卷 / 10期
关键词：
EXHALED NITRIC-OXIDE; NATURAL-RUBBER LATEX; PEAK EXPIRATORY FLOW; BRONCHIAL PROVOCATION TESTS; SKIN PRICK TEST; DIISOCYANATE-INDUCED ASTHMA; INHALATION CHALLENGE TEST; ISOCYANATE-INDUCED ASTHMA; OCCUPATIONAL ASTHMA; INDUCED SPUTUM;
D O I：
10.1097/JOM.0000000000000572
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
Objective: Summarize developed evidence-based diagnostic and treatment guidelines for work-related asthma (WRA). Methods: Comprehensive literature reviews conducted with article critiquing and grading. Guidelines developed by a multidisciplinary expert panel and peer-reviewed. Results: Evidence supports spirometric testing as an essential early test. Serial peak expiratory flow rates measurement is moderately recommended for employees diagnosed with asthma to establish work-relatedness. Bronchial provocation testing is moderately recommended. IgE and skin prick testing for specific high-molecular weight (HMW) antigens are highly recommended. IgG testing for HMW antigens, IgE testing for low-molecular weight antigens, and nitric oxide testing for diagnosis are not recommended. Removal from exposure is associated with the highest probability of improvement, but may not lead to complete recovery. Conclusion: Quality evidence supports these clinical practice recommendations. The guidelines may be useful to providers who diagnose and/or treat WRA.
引用
收藏
页码：E121 / E129
页数：9
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