Photonic crystal microring resonator for labelfree biosensing

被引：105

作者：

Lo, Stanley M. ^{[1
]}

Hu, Shuren ^{[2
]}

Gaur, Girija ^{[1
]}

Kostoulas, Yiorgos ^{[1
]}

Weiss, Sharon M. ^{[1
,2
]}

Fauchet, Philippe M. ^{[1
]}

机构：

[1] Vanderbilt Univ, Dept Elect Engn & Comp Sci, 221 Kirkland Hall, Nashville, TN 37235 USA

[2] Vanderbilt Univ, Dept Phys & Astron, Nashville, TN 37235 USA

来源：

OPTICS EXPRESS | 2017年 / 25卷 / 06期

基金：

美国国家科学基金会;

关键词：

RING-RESONATOR; SLOW-LIGHT; WAVE-GUIDES; SENSITIVITY; DISPERSION; SENSOR; AIR;

D O I：

10.1364/OE.25.007046

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

A label-free optical biosensor based on a one-dimensional photonic crystal microring resonator with enhanced light-matter interaction is demonstrated. More than a 2-fold improvement in volumetric and surface sensing sensitivity is achieved compared to conventional microring sensors. The experimental bulk detection sensitivity is similar to 248nm/RIU and label-free detection of DNA and proteins is reported at the nanomolar scale. With a minimum feature size greater than 100nm, the photonic crystal microring resonator biosensor can be fabricated with the same standard lithographic techniques used to mass fabricate conventional microring resonators. (C) 2017 Optical Society of America

引用

页码：7046 / 7054

页数：9

共 30 条

[1] Nanophotonic waveguides in silicon-on-insulator fabricated with CMOS technology [J].

Bogaerts, W ;

Baets, R ;

Dumon, P ;

Wiaux, V ;

Beckx, S ;

Taillaert, D ;

Luyssaert, B ;

Van Campenhout, J ;

Bienstman, P ;

Van Thourhout, D .

JOURNAL OF LIGHTWAVE TECHNOLOGY, 2005, 23 (01) :401-412

[2] Specific detection of proteins using photonic crystal waveguides [J].

Buswell, S. C. ;

Wright, V. A. ;

Buriak, J. M. ;

Van, V. ;

Evoy, S. .

OPTICS EXPRESS, 2008, 16 (20) :15949-15957

[3] Investigation of refractive index sensing based on Fano resonance in fiber Bragg grating ring resonators [J].

Campanella, Carlo Edoardo ;

De Leonardis, Francesco ;

Mastronardi, Lorenzo ;

Malara, Pietro ;

Gagliardi, Gianluca ;

Passaro, Vittorio M. N. .

OPTICS EXPRESS, 2015, 23 (11) :14301-14313

[4] Slow light engineering for high Q high sensitivity photonic crystal microcavity biosensors in silicon [J].

Chakravarty, Swapnajit ;

Zou, Yi ;

Lai, Wei-Cheng ;

Chen, Ray T. .

BIOSENSORS & BIOELECTRONICS, 2012, 38 (01) :170-176

[5] Label-Free Biosensing With a Slot-Waveguide-Based Ring Resonator in Silicon on Insulator [J].

Claes, Tom ;

Girones Molera, Jordi ;

De Vos, Katrien ;

Schacht, Etienne ;

Baets, Roel ;

Bienstman, Peter .

IEEE PHOTONICS JOURNAL, 2009, 1 (03) :197-204

[6] Performance of SOI Bragg Grating Ring Resonator for Nonlinear Sensing Applications [J].

De Leonardis, Francesco ;

Campanella, Carlo Edoardo ;

Troia, Benedetto ;

Perri, Anna Gina ;

Passaro, Vittorio M. N. .

SENSORS, 2014, 14 (09) :16017-16034

[7] Silicon-on-Insulator microring resonator for sensitive and label-free biosensing [J].

De Vos, Katrien ;

Bartolozzi, Irene ;

Schacht, Etienne ;

Bienstman, Peter ;

Baets, Roel .

OPTICS EXPRESS, 2007, 15 (12) :7610-7615

[8] Sub-wavelength grating for enhanced ring resonator biosensor [J].

Flueckiger, Jonas ;

Schmidt, Shon ;

Donzella, Valentina ;

Sherwali, Ahmed ;

Ratner, Daniel M. ;

Chrostowski, Lukas ;

Cheung, Karen C. .

OPTICS EXPRESS, 2016, 24 (14) :15672-15686

[9] Air-mode photonic crystal ring resonator on silicon-on-insulator [J].

Gao, Ge ;

Zhang, Yong ;

Zhang, He ;

Wang, Yi ;

Huang, Qingzhong ;

Xia, Jinsong .

SCIENTIFIC REPORTS, 2016, 6

[10] Highly dispersive micro-ring resonator based on one dimensional photonic crystal waveguide design and analysis [J].

Goldring, Damian ;

Levy, Uriel ;

Mendlovic, David .

OPTICS EXPRESS, 2007, 15 (06) :3156-3168

← 1 2 3 →