Direction specific release from giant microgel-templated polyelectrolyte microcontainers

被引:49
作者
Bedard, Matthieu F. [2 ,3 ]
De Geest, Bruno G. [1 ]
Moehwald, Helmuth [2 ]
Sukhorukov, Gleb B. [3 ]
Skirtach, Andre G. [2 ]
机构
[1] Univ Ghent, Dept Pharmaceut, B-9000 Ghent, Belgium
[2] Max Planck Inst Colloids & Surfaces, Potsdam, Germany
[3] Queen Mary Univ London, Dept Mat, London, England
关键词
MULTILAYER FILM MORPHOLOGY; ENCAPSULATED MATERIALS; METAL NANOPARTICLES; SWELLING PRESSURE; MICROCAPSULES; HYDROGELS; AGGREGATION; DEGRADATION; ABSORPTION; CAPSULES;
D O I
10.1039/b909919k
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Giant polyelectrolyte microcapsules constructed on dex-HEMA microgel as a sacrificial template and functionalized with gold nanoparticles were found to have the ability to release encapsulated material in a pre-determined direction by selectively irradiating a given region of a capsule's wall with an infrared laser. This technology is envisioned to provide other applications in bio-medicine, an analogue of gene-gun technology on the micro-level for transfecting cells.
引用
收藏
页码:3927 / 3931
页数:5
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