Manganese intoxication

被引:63
作者
Lee, JW [1 ]
机构
[1] Catholic Univ Korea, Coll Med, Dept Neurol, Seoul, South Korea
关键词
D O I
10.1001/archneur.57.4.597
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Manganese plays an important role as a cofactor in many enzymatic reactions in humans but in excess amounts can cause irreversible nervous system damage.(1,2) Although manganism is a rare condition, it can be the cause of complex nervous system symptoms, especially in the setting of environmental exposure.(3,4) Specifically, manganese is a well-known cause of dystonic parkinsonism.(5) This article highlights several historical descriptions of the clinical manifestations, pathological changes, and attempted therapeutic intervention in manganese intoxication.
引用
收藏
页码:597 / 599
页数:3
相关论文
共 23 条
[1]  
AKIKO E, 1992, LANCET, V339, P426
[2]  
BARBEAU A, 1984, NEUROTOXICOLOGY, V5, P13
[3]   MANGANESE INJECTION INTO THE RAT STRIATUM PRODUCES EXCITOTOXIC LESIONS BY IMPAIRING ENERGY-METABOLISM [J].
BROUILLET, EP ;
SHINOBU, L ;
MCGARVEY, U ;
HOCHBERG, F ;
BEAL, MF .
EXPERIMENTAL NEUROLOGY, 1993, 120 (01) :89-94
[4]   MANGANISM AND IDIOPATHIC PARKINSONISM - SIMILARITIES AND DIFFERENCES [J].
CALNE, DB ;
CHU, NS ;
HUANG, CC ;
LU, CS ;
OLANOW, W .
NEUROLOGY, 1994, 44 (09) :1583-1586
[5]   Chronic manganese poisoning - Report of a case, with autopsy [J].
Canavan, MM ;
Cobb, S ;
Drinker, CK .
ARCHIVES OF NEUROLOGY AND PSYCHIATRY, 1934, 32 (03) :501-U11
[6]  
Couper J., 1837, BRIT ANN MED PHARM V, V1, P41, DOI DOI 10.1002/JCP.22692
[7]  
Edsall DL, 1919, J IND HYG, V1, P183
[9]   Manganese toxicity in children receiving long-term parenteral nutrition [J].
Fell, JME ;
Reynolds, AP ;
Meadows, N ;
Khan, K ;
Long, SG ;
Quaghebeur, G ;
Taylor, WJ ;
Milla, PJ .
LANCET, 1996, 347 (9010) :1218-1221
[10]   CHRONIC EXPOSURE TO THE FUNGICIDE MANEB MAY PRODUCE SYMPTOMS AND SIGNS OF CNS MANGANESE INTOXICATION [J].
FERRAZ, HB ;
BERTOLUCCI, PHF ;
PEREIRA, JS ;
LIMA, JGC ;
ANDRADE, LAF .
NEUROLOGY, 1988, 38 (04) :550-553