共 58 条
A murine DC-SIGN homologue contributes to early host defense against Mycobacterium tuberculosis
被引:87
作者:

Tanne, Antoine
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Toulouse 3, Univ Toulouse, Inst Pharmacol & Biol Struct, F-31077 Toulouse, France
Inst Pasteur, Mycobacterial Genet Unit, F-75724 Paris, France
Univ Toulouse 3, Univ Toulouse, CNRS, F-31077 Toulouse, France Univ Toulouse 3, Univ Toulouse, Inst Pharmacol & Biol Struct, F-31077 Toulouse, France

Ma, Bo
论文数: 0 引用数: 0
h-index: 0
机构:
Scripps Res Inst, Dept Physiol Chem, Consortium Funct Glyc, La Jolla, CA 92037 USA Univ Toulouse 3, Univ Toulouse, Inst Pharmacol & Biol Struct, F-31077 Toulouse, France

Boudou, Frederic
论文数: 0 引用数: 0
h-index: 0
机构:
Inst Pasteur, Mycobacterial Genet Unit, F-75724 Paris, France Univ Toulouse 3, Univ Toulouse, Inst Pharmacol & Biol Struct, F-31077 Toulouse, France

Tailleux, Ludovic
论文数: 0 引用数: 0
h-index: 0
机构:
Inst Pasteur, Mycobacterial Genet Unit, F-75724 Paris, France Univ Toulouse 3, Univ Toulouse, Inst Pharmacol & Biol Struct, F-31077 Toulouse, France

Botella, Helene
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Toulouse 3, Univ Toulouse, Inst Pharmacol & Biol Struct, F-31077 Toulouse, France
Univ Toulouse 3, Univ Toulouse, CNRS, F-31077 Toulouse, France Univ Toulouse 3, Univ Toulouse, Inst Pharmacol & Biol Struct, F-31077 Toulouse, France

Badell, Edgar
论文数: 0 引用数: 0
h-index: 0
机构:
Inst Pasteur, Mycobacterial Genet Unit, F-75724 Paris, France Univ Toulouse 3, Univ Toulouse, Inst Pharmacol & Biol Struct, F-31077 Toulouse, France

Levillain, Florence
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Toulouse 3, Univ Toulouse, Inst Pharmacol & Biol Struct, F-31077 Toulouse, France
Univ Toulouse 3, Univ Toulouse, CNRS, F-31077 Toulouse, France Univ Toulouse 3, Univ Toulouse, Inst Pharmacol & Biol Struct, F-31077 Toulouse, France

Taylor, Maureen E.
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h-index: 0
机构:
Univ London Imperial Coll Sci Technol & Med, Div Mol Biosci, London SW7 2AZ, England Univ Toulouse 3, Univ Toulouse, Inst Pharmacol & Biol Struct, F-31077 Toulouse, France

Drickamer, Kurt
论文数: 0 引用数: 0
h-index: 0
机构:
Univ London Imperial Coll Sci Technol & Med, Div Mol Biosci, London SW7 2AZ, England Univ Toulouse 3, Univ Toulouse, Inst Pharmacol & Biol Struct, F-31077 Toulouse, France

Nigou, Jerome
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Toulouse 3, Univ Toulouse, Inst Pharmacol & Biol Struct, F-31077 Toulouse, France
Univ Toulouse 3, Univ Toulouse, CNRS, F-31077 Toulouse, France Univ Toulouse 3, Univ Toulouse, Inst Pharmacol & Biol Struct, F-31077 Toulouse, France

Dobos, Karen M.
论文数: 0 引用数: 0
h-index: 0
机构:
Colorado State Univ, Dept Microbiol Immunol & Pathol, Mycobacteria Res Labs, Ft Collins, CO 80523 USA Univ Toulouse 3, Univ Toulouse, Inst Pharmacol & Biol Struct, F-31077 Toulouse, France

Puzo, Germain
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Toulouse 3, Univ Toulouse, Inst Pharmacol & Biol Struct, F-31077 Toulouse, France
Univ Toulouse 3, Univ Toulouse, CNRS, F-31077 Toulouse, France Univ Toulouse 3, Univ Toulouse, Inst Pharmacol & Biol Struct, F-31077 Toulouse, France

Vestweber, Dietmar
论文数: 0 引用数: 0
h-index: 0
机构:
Max Planck Inst Mol Biomed, D-48149 Munster, Germany Univ Toulouse 3, Univ Toulouse, Inst Pharmacol & Biol Struct, F-31077 Toulouse, France

Wild, Martin K.
论文数: 0 引用数: 0
h-index: 0
机构:
Max Planck Inst Mol Biomed, D-48149 Munster, Germany Univ Toulouse 3, Univ Toulouse, Inst Pharmacol & Biol Struct, F-31077 Toulouse, France

Marcinko, Marie
论文数: 0 引用数: 0
h-index: 0
机构:
Scripps Res Inst, Dept Physiol Chem, Consortium Funct Glyc, La Jolla, CA 92037 USA Univ Toulouse 3, Univ Toulouse, Inst Pharmacol & Biol Struct, F-31077 Toulouse, France

Sobieszczuk, Peter
论文数: 0 引用数: 0
h-index: 0
机构:
Scripps Res Inst, Dept Physiol Chem, Consortium Funct Glyc, La Jolla, CA 92037 USA Univ Toulouse 3, Univ Toulouse, Inst Pharmacol & Biol Struct, F-31077 Toulouse, France

Stewart, Lauren
论文数: 0 引用数: 0
h-index: 0
机构:
Scripps Res Inst, Dept Physiol Chem, Consortium Funct Glyc, La Jolla, CA 92037 USA Univ Toulouse 3, Univ Toulouse, Inst Pharmacol & Biol Struct, F-31077 Toulouse, France

Lebus, Daniel
论文数: 0 引用数: 0
h-index: 0
机构:
Scripps Res Inst, Dept Physiol Chem, Consortium Funct Glyc, La Jolla, CA 92037 USA Univ Toulouse 3, Univ Toulouse, Inst Pharmacol & Biol Struct, F-31077 Toulouse, France

Gicquel, Brigitte
论文数: 0 引用数: 0
h-index: 0
机构:
Inst Pasteur, Mycobacterial Genet Unit, F-75724 Paris, France Univ Toulouse 3, Univ Toulouse, Inst Pharmacol & Biol Struct, F-31077 Toulouse, France

Neyrolles, Olivier
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Toulouse 3, Univ Toulouse, Inst Pharmacol & Biol Struct, F-31077 Toulouse, France
Inst Pasteur, Mycobacterial Genet Unit, F-75724 Paris, France
Univ Toulouse 3, Univ Toulouse, CNRS, F-31077 Toulouse, France Univ Toulouse 3, Univ Toulouse, Inst Pharmacol & Biol Struct, F-31077 Toulouse, France
机构:
[1] Univ Toulouse 3, Univ Toulouse, Inst Pharmacol & Biol Struct, F-31077 Toulouse, France
[2] Inst Pasteur, Mycobacterial Genet Unit, F-75724 Paris, France
[3] Scripps Res Inst, Dept Physiol Chem, Consortium Funct Glyc, La Jolla, CA 92037 USA
[4] Univ London Imperial Coll Sci Technol & Med, Div Mol Biosci, London SW7 2AZ, England
[5] Univ Toulouse 3, Univ Toulouse, CNRS, F-31077 Toulouse, France
[6] Colorado State Univ, Dept Microbiol Immunol & Pathol, Mycobacteria Res Labs, Ft Collins, CO 80523 USA
[7] Max Planck Inst Mol Biomed, D-48149 Munster, Germany
基金:
英国惠康基金;
关键词:
C-TYPE LECTINS;
TOLL-LIKE RECEPTORS;
DENDRITIC CELL;
IMMUNE-RESPONSE;
MICE LACKING;
MOUSE DC;
RECOGNITION;
INFECTION;
DECTIN-1;
MACROPHAGES;
D O I:
10.1084/jem.20090188
中图分类号:
R392 [医学免疫学];
Q939.91 [免疫学];
学科分类号:
100102 ;
摘要:
The C-type lectin dendritic cell-specific intercellular adhesion molecule-3 grabbing nonintegrin (DC-SIGN) mediates the innate immune recognition of microbial carbohydrates. We investigated the function of this molecule in the host response to pathogens in vivo, by generating mouse lines lacking the DC-SIGN homologues SIGNR1, SIGNR3, and SIGNR5. Resistance to Mycobacterium tuberculosis was impaired only in SIGNR3-deficient animals. SIGNR3 was expressed in lung phagocytes during infection, and interacted with M. tuber-culosis bacilli and mycobacterial surface glycoconjugates to induce secretion of critical host defense inflammatory cytokines, including tumor necrosis factor (TNF). SIGNR3 signaling was dependent on an intracellular tyrosine-based motif and the tyrosine kinase Syk. Thus, the mouse DC-SIGN homologue SIGNR3 makes a unique contribution to protection of the host against a pulmonary bacterial pathogen.
引用
收藏
页码:2205 / 2220
页数:16
相关论文
共 58 条
[31]
Recognition of microorganisms and activation of the immune response
[J].
Medzhitov, Ruslan
.
NATURE,
2007, 449 (7164)
:819-826

Medzhitov, Ruslan
论文数: 0 引用数: 0
h-index: 0
机构: Yale Univ, Sch Med, Howard Hughes Med Inst, New Haven, CT 06510 USA
[32]
Towards a crucial role for DC-SIGN in tuberculosis and beyond
[J].
Neyrolles, Olivier
;
Gicquel, Brigitte
;
Quintana-Murci, Lluis
.
TRENDS IN MICROBIOLOGY,
2006, 14 (09)
:383-387

Neyrolles, Olivier
论文数: 0 引用数: 0
h-index: 0
机构: Inst Pasteur, Unit Mycobacterial Genet, F-75015 Paris, France

Gicquel, Brigitte
论文数: 0 引用数: 0
h-index: 0
机构: Inst Pasteur, Unit Mycobacterial Genet, F-75015 Paris, France

Quintana-Murci, Lluis
论文数: 0 引用数: 0
h-index: 0
机构: Inst Pasteur, Unit Mycobacterial Genet, F-75015 Paris, France
[33]
New structural insights into the molecular deciphering of mycobacterial lipoglycan binding to C-type lectins: Lipoarabinomannan glycoform characterization and quantification by capillary electrophoresis at the subnanomole level
[J].
Nigou, J
;
Vercellone, A
;
Puzo, G
.
JOURNAL OF MOLECULAR BIOLOGY,
2000, 299 (05)
:1353-1362

Nigou, J
论文数: 0 引用数: 0
h-index: 0
机构:
CNRS, UPR 9062, Inst Pharmacol & Biol Struct, F-31077 Toulouse 4, France CNRS, UPR 9062, Inst Pharmacol & Biol Struct, F-31077 Toulouse 4, France

Vercellone, A
论文数: 0 引用数: 0
h-index: 0
机构:
CNRS, UPR 9062, Inst Pharmacol & Biol Struct, F-31077 Toulouse 4, France CNRS, UPR 9062, Inst Pharmacol & Biol Struct, F-31077 Toulouse 4, France

Puzo, G
论文数: 0 引用数: 0
h-index: 0
机构:
CNRS, UPR 9062, Inst Pharmacol & Biol Struct, F-31077 Toulouse 4, France CNRS, UPR 9062, Inst Pharmacol & Biol Struct, F-31077 Toulouse 4, France
[34]
Mannan chain length controls lipoglycans signaling via and binding to TLR2
[J].
Nigou, Jerome
;
Vasselon, Thierry
;
Ray, Aurelie
;
Constant, Patricia
;
Gilleron, Martine
;
Besra, Gurdyal S.
;
Sutcliffe, Iain
;
Tiraby, Gerard
;
Puzo, Germain
.
JOURNAL OF IMMUNOLOGY,
2008, 180 (10)
:6696-6702

Nigou, Jerome
论文数: 0 引用数: 0
h-index: 0
机构:
Inst Pharmacol & Biol Struct, Ctr Natl Rech Sci, Unite Mixte Rech 5089, Dept Mol Mech Mycobacterial Infect, F-31077 Toulouse 4, France Inst Pharmacol & Biol Struct, Ctr Natl Rech Sci, Unite Mixte Rech 5089, Dept Mol Mech Mycobacterial Infect, F-31077 Toulouse 4, France

Vasselon, Thierry
论文数: 0 引用数: 0
h-index: 0
机构:
Inst Genet Mol Montpellier, Ctr Natl Rech Sci, Unite Mixte Rech 5535, Montpellier, France Inst Pharmacol & Biol Struct, Ctr Natl Rech Sci, Unite Mixte Rech 5089, Dept Mol Mech Mycobacterial Infect, F-31077 Toulouse 4, France

Ray, Aurelie
论文数: 0 引用数: 0
h-index: 0
机构:
Inst Pharmacol & Biol Struct, Ctr Natl Rech Sci, Unite Mixte Rech 5089, Dept Mol Mech Mycobacterial Infect, F-31077 Toulouse 4, France Inst Pharmacol & Biol Struct, Ctr Natl Rech Sci, Unite Mixte Rech 5089, Dept Mol Mech Mycobacterial Infect, F-31077 Toulouse 4, France

Constant, Patricia
论文数: 0 引用数: 0
h-index: 0
机构:
Inst Pharmacol & Biol Struct, Ctr Natl Rech Sci, Unite Mixte Rech 5089, Dept Mol Mech Mycobacterial Infect, F-31077 Toulouse 4, France Inst Pharmacol & Biol Struct, Ctr Natl Rech Sci, Unite Mixte Rech 5089, Dept Mol Mech Mycobacterial Infect, F-31077 Toulouse 4, France

Gilleron, Martine
论文数: 0 引用数: 0
h-index: 0
机构:
Inst Pharmacol & Biol Struct, Ctr Natl Rech Sci, Unite Mixte Rech 5089, Dept Mol Mech Mycobacterial Infect, F-31077 Toulouse 4, France Inst Pharmacol & Biol Struct, Ctr Natl Rech Sci, Unite Mixte Rech 5089, Dept Mol Mech Mycobacterial Infect, F-31077 Toulouse 4, France

Besra, Gurdyal S.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Birmingham, Sch Biosci, Birmingham B15 2TT, W Midlands, England Inst Pharmacol & Biol Struct, Ctr Natl Rech Sci, Unite Mixte Rech 5089, Dept Mol Mech Mycobacterial Infect, F-31077 Toulouse 4, France

Sutcliffe, Iain
论文数: 0 引用数: 0
h-index: 0
机构:
Northumbria Univ, Sch Appl Sci, Newcastle Upon Tyne NE1 8ST, Tyne & Wear, England Inst Pharmacol & Biol Struct, Ctr Natl Rech Sci, Unite Mixte Rech 5089, Dept Mol Mech Mycobacterial Infect, F-31077 Toulouse 4, France

Tiraby, Gerard
论文数: 0 引用数: 0
h-index: 0
机构:
Cayla Invivogen, Res Dept, Toulouse, France Inst Pharmacol & Biol Struct, Ctr Natl Rech Sci, Unite Mixte Rech 5089, Dept Mol Mech Mycobacterial Infect, F-31077 Toulouse 4, France

Puzo, Germain
论文数: 0 引用数: 0
h-index: 0
机构:
Inst Pharmacol & Biol Struct, Ctr Natl Rech Sci, Unite Mixte Rech 5089, Dept Mol Mech Mycobacterial Infect, F-31077 Toulouse 4, France Inst Pharmacol & Biol Struct, Ctr Natl Rech Sci, Unite Mixte Rech 5089, Dept Mol Mech Mycobacterial Infect, F-31077 Toulouse 4, France
[35]
Five mouse homologues of the human dendritic cell C-type lectin, DC-SIGN
[J].
Park, CG
;
Takahara, K
;
Umemoto, E
;
Yashima, Y
;
Matsubara, K
;
Matsuda, Y
;
Clausen, BE
;
Inaba, K
;
Steinman, RM
.
INTERNATIONAL IMMUNOLOGY,
2001, 13 (10)
:1283-1290

Park, CG
论文数: 0 引用数: 0
h-index: 0
机构: Rockefeller Univ, Cellular Physiol & Immunol Lab, New York, NY 10021 USA

Takahara, K
论文数: 0 引用数: 0
h-index: 0
机构: Rockefeller Univ, Cellular Physiol & Immunol Lab, New York, NY 10021 USA

Umemoto, E
论文数: 0 引用数: 0
h-index: 0
机构: Rockefeller Univ, Cellular Physiol & Immunol Lab, New York, NY 10021 USA

Yashima, Y
论文数: 0 引用数: 0
h-index: 0
机构: Rockefeller Univ, Cellular Physiol & Immunol Lab, New York, NY 10021 USA

Matsubara, K
论文数: 0 引用数: 0
h-index: 0
机构: Rockefeller Univ, Cellular Physiol & Immunol Lab, New York, NY 10021 USA

Matsuda, Y
论文数: 0 引用数: 0
h-index: 0
机构: Rockefeller Univ, Cellular Physiol & Immunol Lab, New York, NY 10021 USA

Clausen, BE
论文数: 0 引用数: 0
h-index: 0
机构: Rockefeller Univ, Cellular Physiol & Immunol Lab, New York, NY 10021 USA

Inaba, K
论文数: 0 引用数: 0
h-index: 0
机构: Rockefeller Univ, Cellular Physiol & Immunol Lab, New York, NY 10021 USA

Steinman, RM
论文数: 0 引用数: 0
h-index: 0
机构: Rockefeller Univ, Cellular Physiol & Immunol Lab, New York, NY 10021 USA
[36]
Deciphering the molecular bases of Mycobacterium tuberculosis binding to the lectin DC-SIGN reveals an underestimated complexity
[J].
Pitarque, S
;
Herrmann, JL
;
Duteyrat, JL
;
Jackson, M
;
Stewart, GR
;
Lecointe, F
;
Payre, B
;
Schwartz, O
;
Young, DB
;
Marchal, G
;
Lagrange, PH
;
Puzo, G
;
Gicquel, B
;
Nigou, J
;
Neyrolles, O
.
BIOCHEMICAL JOURNAL,
2005, 392
:615-624

Pitarque, S
论文数: 0 引用数: 0
h-index: 0
机构: CNRS, Inst Pharmacol & Biol Struct, Dept Mecan Mol Infect Mycobacteriennes, UMR 5089, F-31077 Toulouse 4, France

Herrmann, JL
论文数: 0 引用数: 0
h-index: 0
机构: CNRS, Inst Pharmacol & Biol Struct, Dept Mecan Mol Infect Mycobacteriennes, UMR 5089, F-31077 Toulouse 4, France

Duteyrat, JL
论文数: 0 引用数: 0
h-index: 0
机构: CNRS, Inst Pharmacol & Biol Struct, Dept Mecan Mol Infect Mycobacteriennes, UMR 5089, F-31077 Toulouse 4, France

Jackson, M
论文数: 0 引用数: 0
h-index: 0
机构: CNRS, Inst Pharmacol & Biol Struct, Dept Mecan Mol Infect Mycobacteriennes, UMR 5089, F-31077 Toulouse 4, France

Stewart, GR
论文数: 0 引用数: 0
h-index: 0
机构: CNRS, Inst Pharmacol & Biol Struct, Dept Mecan Mol Infect Mycobacteriennes, UMR 5089, F-31077 Toulouse 4, France

Lecointe, F
论文数: 0 引用数: 0
h-index: 0
机构: CNRS, Inst Pharmacol & Biol Struct, Dept Mecan Mol Infect Mycobacteriennes, UMR 5089, F-31077 Toulouse 4, France

Payre, B
论文数: 0 引用数: 0
h-index: 0
机构: CNRS, Inst Pharmacol & Biol Struct, Dept Mecan Mol Infect Mycobacteriennes, UMR 5089, F-31077 Toulouse 4, France

Schwartz, O
论文数: 0 引用数: 0
h-index: 0
机构: CNRS, Inst Pharmacol & Biol Struct, Dept Mecan Mol Infect Mycobacteriennes, UMR 5089, F-31077 Toulouse 4, France

Young, DB
论文数: 0 引用数: 0
h-index: 0
机构: CNRS, Inst Pharmacol & Biol Struct, Dept Mecan Mol Infect Mycobacteriennes, UMR 5089, F-31077 Toulouse 4, France

Marchal, G
论文数: 0 引用数: 0
h-index: 0
机构: CNRS, Inst Pharmacol & Biol Struct, Dept Mecan Mol Infect Mycobacteriennes, UMR 5089, F-31077 Toulouse 4, France

Lagrange, PH
论文数: 0 引用数: 0
h-index: 0
机构: CNRS, Inst Pharmacol & Biol Struct, Dept Mecan Mol Infect Mycobacteriennes, UMR 5089, F-31077 Toulouse 4, France

Puzo, G
论文数: 0 引用数: 0
h-index: 0
机构: CNRS, Inst Pharmacol & Biol Struct, Dept Mecan Mol Infect Mycobacteriennes, UMR 5089, F-31077 Toulouse 4, France

Gicquel, B
论文数: 0 引用数: 0
h-index: 0
机构: CNRS, Inst Pharmacol & Biol Struct, Dept Mecan Mol Infect Mycobacteriennes, UMR 5089, F-31077 Toulouse 4, France

Nigou, J
论文数: 0 引用数: 0
h-index: 0
机构: CNRS, Inst Pharmacol & Biol Struct, Dept Mecan Mol Infect Mycobacteriennes, UMR 5089, F-31077 Toulouse 4, France

Neyrolles, O
论文数: 0 引用数: 0
h-index: 0
机构: CNRS, Inst Pharmacol & Biol Struct, Dept Mecan Mol Infect Mycobacteriennes, UMR 5089, F-31077 Toulouse 4, France
[37]
Widely divergent biochemical properties of the complete set of mouse DC-SIGN-related proteins
[J].
Powlesland, Alex S.
;
Ward, Eliot M.
;
Sadhu, Sumon K.
;
Guo, Yuan
;
Taylor, Maureen E.
;
Drickamer, Kurt
.
JOURNAL OF BIOLOGICAL CHEMISTRY,
2006, 281 (29)
:20440-20449

Powlesland, Alex S.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ London Imperial Coll Sci & Technol, Div Mol Biosci, London SW7 2AZ, England Univ London Imperial Coll Sci & Technol, Div Mol Biosci, London SW7 2AZ, England

Ward, Eliot M.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ London Imperial Coll Sci & Technol, Div Mol Biosci, London SW7 2AZ, England Univ London Imperial Coll Sci & Technol, Div Mol Biosci, London SW7 2AZ, England

Sadhu, Sumon K.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ London Imperial Coll Sci & Technol, Div Mol Biosci, London SW7 2AZ, England Univ London Imperial Coll Sci & Technol, Div Mol Biosci, London SW7 2AZ, England

Guo, Yuan
论文数: 0 引用数: 0
h-index: 0
机构:
Univ London Imperial Coll Sci & Technol, Div Mol Biosci, London SW7 2AZ, England Univ London Imperial Coll Sci & Technol, Div Mol Biosci, London SW7 2AZ, England

Taylor, Maureen E.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ London Imperial Coll Sci & Technol, Div Mol Biosci, London SW7 2AZ, England Univ London Imperial Coll Sci & Technol, Div Mol Biosci, London SW7 2AZ, England

Drickamer, Kurt
论文数: 0 引用数: 0
h-index: 0
机构:
Univ London Imperial Coll Sci & Technol, Div Mol Biosci, London SW7 2AZ, England Univ London Imperial Coll Sci & Technol, Div Mol Biosci, London SW7 2AZ, England
[38]
Regulated expression of the pathogen receptor dendritic cell-specific intercellular adhesion molecule 3 (ICAM-3)-grabbing nonintegrin in THP-1 human leukemic cells, monocytes, and macrophages
[J].
Puig-Kröger, A
;
Serrano-Gómez, D
;
Caparrós, E
;
Domínguez-Soto, A
;
Relloso, M
;
Colmenares, M
;
Martínez-Muñoz, L
;
Longo, N
;
Sánchez-Sánchez, N
;
Rincon, M
;
Rivas, L
;
Sánchez-Mateos, P
;
Fernández-Ruiz, E
;
Corbi, AL
.
JOURNAL OF BIOLOGICAL CHEMISTRY,
2004, 279 (24)
:25680-25688

Puig-Kröger, A
论文数: 0 引用数: 0
h-index: 0
机构: CSIC, Ctr Invest Biol, Madrid 28040, Spain

Serrano-Gómez, D
论文数: 0 引用数: 0
h-index: 0
机构: CSIC, Ctr Invest Biol, Madrid 28040, Spain

Caparrós, E
论文数: 0 引用数: 0
h-index: 0
机构: CSIC, Ctr Invest Biol, Madrid 28040, Spain

Domínguez-Soto, A
论文数: 0 引用数: 0
h-index: 0
机构: CSIC, Ctr Invest Biol, Madrid 28040, Spain

Relloso, M
论文数: 0 引用数: 0
h-index: 0
机构: CSIC, Ctr Invest Biol, Madrid 28040, Spain

Colmenares, M
论文数: 0 引用数: 0
h-index: 0
机构: CSIC, Ctr Invest Biol, Madrid 28040, Spain

Martínez-Muñoz, L
论文数: 0 引用数: 0
h-index: 0
机构: CSIC, Ctr Invest Biol, Madrid 28040, Spain

Longo, N
论文数: 0 引用数: 0
h-index: 0
机构: CSIC, Ctr Invest Biol, Madrid 28040, Spain

Sánchez-Sánchez, N
论文数: 0 引用数: 0
h-index: 0
机构: CSIC, Ctr Invest Biol, Madrid 28040, Spain

Rincon, M
论文数: 0 引用数: 0
h-index: 0
机构: CSIC, Ctr Invest Biol, Madrid 28040, Spain

Rivas, L
论文数: 0 引用数: 0
h-index: 0
机构: CSIC, Ctr Invest Biol, Madrid 28040, Spain

Sánchez-Mateos, P
论文数: 0 引用数: 0
h-index: 0
机构: CSIC, Ctr Invest Biol, Madrid 28040, Spain

Fernández-Ruiz, E
论文数: 0 引用数: 0
h-index: 0
机构: CSIC, Ctr Invest Biol, Madrid 28040, Spain

Corbi, AL
论文数: 0 引用数: 0
h-index: 0
机构: CSIC, Ctr Invest Biol, Madrid 28040, Spain
[39]
Immunology in natura: clinical, epidemiological and evolutionary genetics of infectious diseases
[J].
Quintana-Murci, Lluis
;
Alcais, Alexandre
;
Abel, Laurent
;
Casanova, Jean-Laurent
.
NATURE IMMUNOLOGY,
2007, 8 (11)
:1165-1171

Quintana-Murci, Lluis
论文数: 0 引用数: 0
h-index: 0
机构: Necker Med Sch, INSERM, Lab Human Genet Infect Dis, U550, F-75015 Paris, France

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Casanova, Jean-Laurent
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机构:
Necker Med Sch, INSERM, Lab Human Genet Infect Dis, U550, F-75015 Paris, France Necker Med Sch, INSERM, Lab Human Genet Infect Dis, U550, F-75015 Paris, France
[40]
Cutting edge:: Toll-like receptor (TLR)2- and TLR4-mediated pathogen recognition in resistance to airborne infection with Mycobacterium tuberculosis
[J].
Reiling, N
;
Hölscher, C
;
Fehrenbach, A
;
Kröger, S
;
Kirschning, CJ
;
Goyert, S
;
Ehlers, S
.
JOURNAL OF IMMUNOLOGY,
2002, 169 (07)
:3480-3484

Reiling, N
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机构: Res Ctr Borstel, Div Mol Infect Biol, D-23845 Borstel, Germany

Hölscher, C
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机构: Res Ctr Borstel, Div Mol Infect Biol, D-23845 Borstel, Germany

Fehrenbach, A
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机构: Res Ctr Borstel, Div Mol Infect Biol, D-23845 Borstel, Germany

Kröger, S
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机构: Res Ctr Borstel, Div Mol Infect Biol, D-23845 Borstel, Germany

Kirschning, CJ
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机构: Res Ctr Borstel, Div Mol Infect Biol, D-23845 Borstel, Germany

Goyert, S
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机构: Res Ctr Borstel, Div Mol Infect Biol, D-23845 Borstel, Germany

Ehlers, S
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机构: Res Ctr Borstel, Div Mol Infect Biol, D-23845 Borstel, Germany