Renal Resistive Index and mortality in critical patients with acute kidney injury

被引:39
|
作者
Boddi, Maria [1 ]
Bonizzoli, Manuela [2 ]
Chiostri, Marco [1 ]
Begliomini, Dario [2 ]
Molinaro, Adele [2 ]
Buoninsegni, Laura Tadini [2 ]
Gensini, Gian Franco [1 ,3 ]
Peris, Adriano [2 ]
机构
[1] Univ Florence, Expt & Clin Med Dept, Viale Morgagni 85, I-50134 Florence, Italy
[2] Careggi Teaching Hosp, Anaesthesia & Intens Care Unit, Emergency Dept, Florence, Italy
[3] Don Carlo Gnocchi Fdn, IRCCS, Florence, Italy
关键词
Acute kidney injury; intensive care; renal function; renal resistive index; ultrasonography; ILL PATIENTS; REPLACEMENT THERAPY; SEPTIC SHOCK; FAILURE; EPIDEMIOLOGY; PREDICTION; RESISTANCE; DIALYSIS; OUTCOMES; RIFLE;
D O I
10.1111/eci.12590
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
BackgroundThe predictive role of Doppler Renal Resistive Index (RRI) for mortality was shown in chronic kidney disease. In selected populations of intensive care unit (ICU), RRI predicts acute kidney injury (AKI) occurrence and anticipates persistent AKI. No data are available about mortality. We investigated whether RRI assay at AKI diagnosis could predict AKI mortality in a 10-bed-mixed medical-surgical and trauma ICU of a tertiary referral teaching hospital. The association between RRI and persistent AKI at discharge was investigated. MethodsOne hundred and twenty-five of 1512 patients admitted from January 2010 to March 2013 who developed AKI during ICU stay were enrolled. Kidney function was evaluated daily according to risk, injury, failure, loss and end-stage criteria. At AKI diagnosis, we measured RRI. The association between RRI at AKI diagnosis and ICU death or persistent AKI at ICU discharge was analysed by multivariable logistic regression analysis. ResultsAt AKI diagnosis, RRI was 077 (070-088) in survivors and 085 in nonsurvivors (079-094) (P=0002). RRI values were significantly associated with ICU death (OR=163-95% CI 106-249, P=0025). A RRI cut-off value of 077 was identified by receiver operating characteristic curve. Multivariate analysis selected RRI and abdominal hypertension as strongest predictors of AKI mortality. At AKI diagnosis, RRI was 078 (070-085) or 085 (073-092) (P=0026) in patients with or without persistent AKI at discharge. Multivariate analysis selected RRI at AKI diagnosis as the strongest predictor of persistent AKI. ConclusionsHigh RRI values at AKI diagnosis are strictly and independently associated with in-ICU mortality and persistent AKI at ICU discharge.
引用
收藏
页码:242 / 251
页数:10
相关论文
共 50 条
  • [1] Renal Resistive Index as a Predictor of Acute Kidney Injury and Mortality in COVID-19 Critically Ill Patients
    Cruz, Edgar Garcia
    Broca Garcia, Blanca Estela
    Sandoval, Daniel Manzur
    Gopar-Nieto, Rodrigo
    Gonzalez Ruiz, Francisco Javier
    Gallardo, Linda Diaz
    Ronco, Claudio
    Madero, Magdalena
    Vasquez Jimenez, Enzo
    BLOOD PURIFICATION, 2022, 51 (04) : 309 - 316
  • [2] Intraoperative renal resistive index threshold as an acute kidney injury biomarker
    Cherry, Anne D.
    Hauck, Jennifer N.
    Andrew, Benjamin Y.
    Li, Yi-Ju
    Privratsky, Jamie R.
    Kartha, Lakshmi D.
    Nicoara, Alina
    Thompson, Annemarie
    Mathew, Joseph P.
    Stafford-Smith, Mark
    JOURNAL OF CLINICAL ANESTHESIA, 2020, 61
  • [3] Renal Resistive Index as A Potential Indicator of Acute Kidney Injury in Horses
    Siwinska, Natalia
    Zak, Agnieszka
    Slowikowska, Malwina
    Paslawska, Urszula
    JOURNAL OF EQUINE VETERINARY SCIENCE, 2021, 103
  • [4] Renal resistive index as a biomarker for acute kidney injury in aortic valve surgery
    Thin Xuan Vo
    Boodhwani, Munir
    JOURNAL OF THORACIC DISEASE, 2018, 10 : S4010 - S4012
  • [5] Utility of renal resistive index as an early marker of acute kidney injury related to intra-abdominal pressure in critical ill patients
    P Ortiz Ballujera
    C Vera Ching
    J Calabia Martinez
    C Molina Rodriguez
    A Marin Valencia
    J Gonzalez Londoño
    JM Sirvent
    Intensive Care Medicine Experimental, 3 (Suppl 1)
  • [6] Diagnostic accuracy of Doppler renal resistive index for reversibility of acute kidney injury in critically ill patients
    Darmon, Michael
    Schortgen, Frederique
    Vargas, Frederic
    Liazydi, Aissam
    Schlemmer, Benoit
    Brun-Buisson, Christian
    Brochard, Laurent
    INTENSIVE CARE MEDICINE, 2011, 37 (01) : 68 - 76
  • [7] Renal Resistive Index and Mortality in Chronic Kidney Disease
    Toledo, Clarisse
    Thomas, George
    Schold, Jesse D.
    Arrigain, Susana
    Gornik, Heather L.
    Nally, Joseph V.
    Navaneethan, Sankar D.
    HYPERTENSION, 2015, 66 (02) : 382 - 388
  • [8] Diagnostic accuracy of Doppler renal resistive index for reversibility of acute kidney injury in critically ill patients
    Michael Darmon
    Frédérique Schortgen
    Frederic Vargas
    Aissam Liazydi
    Benoît Schlemmer
    Christian Brun-Buisson
    Laurent Brochard
    Intensive Care Medicine, 2011, 37 : 68 - 76
  • [9] Preoperative Renal Resistive Index Predicts Risk of Acute Kidney Injury in Patients Undergoing Cardiac Surgery
    Hertzberg, Daniel
    Ceder, Simon L.
    Sartipy, Ulrik
    Lund, Kent
    Holzmann, Martin J.
    JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA, 2017, 31 (03) : 847 - 852
  • [10] Renal-Resistive Index for Prediction of Acute Kidney Injury in the Setting of Aortic Insufficiency
    Gosling, Andre F.
    Andrew, Benjamin Y.
    Stafford-Smith, Mark
    Nicoara, Alina
    Cherry, Anne D.
    JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA, 2021, 35 (12) : 3819 - 3825