No association between socio-economic status and white blood cell telomere length

被引:68
作者
Adams, Jean
Martin-Ruiz, Carmen
Pearce, Mark S.
White, Martin
Parker, Louise
von Zglinicki, Thomas [1 ]
机构
[1] Univ Newcastle Upon Tyne, Newcastle Gen Hosp, Henry Wellcome Lab Biogerontol Res, Inst Ageing & Hlth, Newcastle Upon Tyne NE4 6BE, Tyne & Wear, England
[2] Univ Newcastle Upon Tyne, Inst Hlth & Soc, Newcastle Upon Tyne NE2 4AA, Tyne & Wear, England
[3] Univ Newcastle Upon Tyne, Sch Clin Med Sci, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England
基金
英国医学研究理事会; 英国惠康基金;
关键词
biological aging; inequalities; Newcastle Thousand Families; socio-economic factors;
D O I
10.1111/j.1474-9726.2006.00258.x
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
It has been hypothesized that more socio-economically deprived individuals age faster and, thus, have shorter telomeres than their more affluent counterparts. A weak association between white blood cell telomere length and socio-economic status in a large heterogeneous sample of females has recently been reported. In 318 individuals from a homogeneous birth cohort, we found no evidence of an association between any measure of socio-economic status and peripheral blood mononucleocyte telomere length at age 50 after control for lifestyle variables, gender and paternal age at birth. The results of this, and the previous study, suggest that there is little evidence of a strong or consistent correlation between white blood cell telomere length and markers of socio-economic status.
引用
收藏
页码:125 / 128
页数:4
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