Brentuximab vedotin in relapsed primary mediastinal large B-cell lymphoma: results from a phase 2 clinical trial

被引:84
作者
Zinzani, Pier Luigi [1 ]
Pellegrini, Cinzia [1 ]
Chiappella, Annalisa [2 ]
Di Rocco, Alice [3 ]
Salvi, Flavia [4 ]
Cabras, Maria Giuseppina [5 ]
Argnani, Lisa [1 ]
Stefoni, Vittorio [1 ]
机构
[1] Univ Bologna, Inst Hematol LeA Seragnoli, Via Massarenti 9, I-40138 Bologna, Italy
[2] Citta Salute & Sci Hosp & Univ, Hematol Unit, Turin, Italy
[3] Sapienza Univ, Dept Cellular Biotechnol & Hematol, Rome, Italy
[4] Osped SS Antonio & Biagio Alessandria, Dept Hematol, Alessandria, Italy
[5] Azienda Osped Brotzu, A Businco Canc Hosp, Hematol & Bone Marrow Transplantat Unit, Cagliari, Italy
关键词
HIGH-DOSE CHEMOTHERAPY; HODGKIN LYMPHOMA; TRANSPLANTATION; THERAPY;
D O I
10.1182/blood-2017-01-764258
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:2328 / 2330
页数:5
相关论文
共 16 条
[1]  
[Anonymous], 2013, ASH ANN M
[2]   High-dose chemotherapy followed by autologous stem cell transplantation for relapsed/refractory primary mediastinal large B-cell lymphoma [J].
Aoki, T. ;
Shimada, K. ;
Suzuki, R. ;
Izutsu, K. ;
Tomita, A. ;
Maeda, Y. ;
Takizawa, J. ;
Mitani, K. ;
Igarashi, T. ;
Sakai, K. ;
Miyazaki, K. ;
Mihara, K. ;
Ohmachi, K. ;
Nakamura, N. ;
Takasaki, H. ;
Kiyoi, H. ;
Nakamura, S. ;
Kinoshita, T. ;
Ogura, M. .
BLOOD CANCER JOURNAL, 2015, 5 :e372-e372
[3]   Revised response criteria for malignant lymphoma [J].
Cheson, Bruce D. ;
Pfistner, Beate ;
Juweid, Malik E. ;
Gascoyne, Randy D. ;
Specht, Lena ;
Horning, Sandra J. ;
Coiffier, Bertrand ;
Fisher, Richard I. ;
Hagenbeek, Anton ;
Zucca, Emanuele ;
Rosen, Steven T. ;
Stroobants, Sigrid ;
Lister, T. Andrew ;
Hoppe, Richard T. ;
Dreyling, Martin ;
Tobinai, Kensei ;
Vose, Julie M. ;
Connors, Joseph M. ;
Federico, Massimo ;
Diehl, Volker .
JOURNAL OF CLINICAL ONCOLOGY, 2007, 25 (05) :579-586
[4]   Dose-Adjusted EPOCH-Rituximab Therapy in Primary Mediastinal B-Cell Lymphoma [J].
Dunleavy, Kieron ;
Pittaluga, Stefania ;
Maeda, Lauren S. ;
Advani, Ranjana ;
Chen, Clara C. ;
Hessler, Julie ;
Steinberg, Seth M. ;
Grant, Cliona ;
Wright, George ;
Varma, Gaurav ;
Staudt, Louis M. ;
Jaffe, Elaine S. ;
Wilson, Wyndham H. .
NEW ENGLAND JOURNAL OF MEDICINE, 2013, 368 (15) :1408-1416
[5]   Primary mediastinal large B-cell lymphoma: optimal therapy and prognostic factor analysis in 141 consecutive patients treated at Memorial Sloan Kettering from 1980 to 1999 [J].
Hamlin, PA ;
Portlock, CS ;
Straus, DJ ;
Noy, A ;
Singer, A ;
Horwitz, SM ;
OConnor, OA ;
Yahalom, J ;
Zelenetz, AD ;
Moskowitz, CH .
BRITISH JOURNAL OF HAEMATOLOGY, 2005, 130 (05) :691-699
[6]   Brentuximab vedotin demonstrates objective responses in a phase 2 study of relapsed/refractory DLBCL with variable CD30 expression [J].
Jacobsen, Eric D. ;
Sharman, Jeff P. ;
Oki, Yasuhiro ;
Advani, Ranjana H. ;
Winter, Jane N. ;
Bello, Celeste M. ;
Spitzer, Gary ;
Palanca-Wessels, Maria Corinna ;
Kennedy, Dana A. ;
Levine, Pamela ;
Yang, Jing ;
Bartlett, Nancy L. .
BLOOD, 2015, 125 (09) :1394-1402
[7]   Salvage chemotherapy and autologous stem cell transplantation are inferior for relapsed or refractory primary mediastinal large B-cell lymphoma compared with diffuse large B-cell lymphoma [J].
Kuruvilla, John ;
Pintilie, Melania ;
Tsang, Richard ;
Nagy, Tracy ;
Keating, Armand ;
Crump, Michael .
LEUKEMIA & LYMPHOMA, 2008, 49 (07) :1329-1336
[8]   Primary mediastinal B-cell lymphoma treated with CHOP-like chemotherapy with or without rituximab: results of the Mabthera International Trial Group study [J].
Rieger, M. ;
Osterborg, A. ;
Pettengell, R. ;
White, D. ;
Gill, D. ;
Walewski, J. ;
Kuhnt, E. ;
Loeffler, M. ;
Pfreundschuh, M. ;
Ho, A. D. .
ANNALS OF ONCOLOGY, 2011, 22 (03) :664-670
[9]   Primary mediastinal large cell lymphoma (PMBL):: frontline treatment with autologous stem cell transplantation (ASCT).: The GEL-TAMO experience [J].
Rodriguez, Jose ;
Conde, Eulogio ;
Gutierrez, Antonio ;
Carlos Garcia, Juan ;
Jose Lahuerta, Juan ;
Rosario Varela, Maria ;
Perez, Catalina ;
Albo, Carmen ;
Dolores Caballero, Mana .
HEMATOLOGICAL ONCOLOGY, 2008, 26 (03) :171-178
[10]   Molecular diagnosis of primary mediastinal B cell lymphoma identifies a clinically favorable subgroup of diffuse large B cell lymphoma related to Hodgkin lymphoma [J].
Rosenwald, A ;
Wright, G ;
Leroy, K ;
Yu, X ;
Gaulard, P ;
Gascoyne, RD ;
Chan, WC ;
Zhao, T ;
Haioun, C ;
Greiner, TC ;
Weisenburger, DD ;
Lynch, JC ;
Vose, J ;
Armitage, JO ;
Smeland, EB ;
Kvaloy, S ;
Holte, H ;
Delabie, J ;
Campo, E ;
Montserrat, E ;
Lopez-Guillermo, A ;
Ott, G ;
Muller-Hermelink, HK ;
Connors, JM ;
Braziel, R ;
Grogan, TM ;
Fisher, RI ;
Miller, TP ;
LeBlanc, M ;
Chiorazzi, M ;
Zhao, H ;
Yang, LM ;
Powell, J ;
Wilson, WH ;
Jaffe, ES ;
Simon, R ;
Klausner, RD ;
Staudt, LM .
JOURNAL OF EXPERIMENTAL MEDICINE, 2003, 198 (06) :851-862