Proteolysis in the SOS response and metal homeostasis in Escherichia coli

被引:21
作者
Pruteanu, Mihaela [1 ,2 ]
Baker, Tania A. [1 ,2 ]
机构
[1] MIT, Howard Hughes Med Inst, Cambridge, MA 02139 USA
[2] MIT, Dept Biol, Cambridge, MA 02139 USA
关键词
ClpXP; Metal homeostasis; Proteolysis; SOS response; NUCLEOTIDE EXCISION-REPAIR; CLPX-RECOGNITION SIGNALS; COUPLED DNA-REPAIR; TRANSCRIPTIONAL REGULATOR; SPONTANEOUS MUTAGENESIS; CELL-DIVISION; PROTEASE; DEGRADATION; PROTEINS; GENE;
D O I
10.1016/j.resmic.2009.08.012
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Proteolysis is used by all forms of life for shaping the proteome in response to adverse environmental conditions in order to ensure optimal survival. Here we will address the role of proteolysis in helping cells respond to environmental stress, with a focus on the impact of proteolysis under DNA-damaging conditions and in maintenance of cellular homeostasis in response to metal exposure in bacteria. (C) 2009 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码:677 / 683
页数:7
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