A new and facile synthesis of imidazo[2,1-b]oxazoles

被引：9

作者：

Mekonnen, B ^{[1
]}

Crank, G ^{[1
]}

Craig, D ^{[1
]}

机构：

[1] UNIV NEW S WALES, SCH CHEM, SYDNEY, NSW 2052, AUSTRALIA

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1997年 / 34卷 / 02期

关键词：

D O I：

10.1002/jhet.5570340241

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient and clean two step procedure for the synthesis of imidazo[2,1-b]oxazoles has been developed from 2-aminooxazoles using titanium(IV) chloride assisted cyclization, and a variety of imidazo[2,1-b]oxazoles have been synthesized in good yields. The structure of one of the products was confirmed by X-ray crystallographic analysis.

引用

页码：589 / 599

页数：11

共 50 条

[41] New imidazo[2,1-b]thiazole derivatives: Synthesis, in vitro anticancer evaluation, and in silico studies [J].

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[42] Design, synthesis and biological evaluation of imidazo[2,1-b]thiazole and benzo[d]imidazo[2,1-b]thiazole derivatives as Mycobacterium tuberculosis pantothenate synthetase inhibitors [J].

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Devi, Parthiban Brindha ;

Saxena, Shalini ;

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Yogeeswari, Perumal ;

Sriram, Dharmarajan .

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[43] Synthesis of new functionalized imidazo[2,1-b]thiazoles and thiazolo[3,2-a]pyrimidines [J].

Peterlin-Masic, L ;

Malesic, M ;

Breznik, M ;

Krbavcic, A .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 2000, 37 (01) :95-101

[44] Synthesis and X-ray structure of new spiro-imidazo[2,1-b]thiazole [J].

Feng, YQ ;

Zhang, WH ;

Chen, LG ;

Froelich, J ;

Meretter, K ;

Sauter, F .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 1999, 36 (05) :1307-1310

[45] REACTIONS OF 5-ARYLIDENE-2-THIOHYDANTOINS - SYNTHESIS OF NEW CONDENSED IMIDAZO[2,1-B]THIAZOLES [J].

DABOUN, HA ;

ABDELFATTAH, AM ;

HUSSEIN, MM ;

SHALABY, AFA .

POLISH JOURNAL OF CHEMISTRY, 1982, 56 (7-9) :1001-1007

[46] IMIDAZO[2,1-B]BENZOTHIAZOLES .3. SYNTHESES AND IMMUNOSUPPRESSIVE ACTIVITIES OF 2-(META-ACYLOXYPHENYL)IMIDAZO[2,1-B]BENZOTHIAZOLES [J].

MASE, T ;

ARIMA, H ;

TOMIOKA, K ;

YAMADA, T ;

MURASE, K .

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 1988, 23 (04) :335-339

[47] NEW SYNTHESIS OF NAPHTHO[2,1-B] FURAN [J].

KITO, T ;

OTA, K ;

HARADA, Y .

JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN, 1978, 36 (01) :70-71

[48] Imidazo[2,1-b]thiazoles, imidazo[2,1-b]imidazoles and pyrrolo[1,2-c]imidazoles.: Synthesis, structure and evaluation of benzodiazepine receptor binding [J].

Kiec-Kononowicz, K ;

Müller, CE ;

Pekala, E ;

Karolak-Wojciechowska, J ;

Handzlik, J ;

Lazewska, D .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 2002, 39 (02) :243-253

[49] Intramolecular amidation:: synthesis of novel imidazo[2,1-b][1,3,4]thiadiazole and imidazo[2,1-b][1,3]thiazole fused diazepinones [J].

Kolavi, G ;

Hegde, V ;

Khazi, IA .

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[50] HETEROCYCLIC-SYSTEMS CONTAINING BRIDGEHEAD NITROGEN ATOM - SYNTHESIS OF IMIDAZO [2,1-B]-BENZOTHIAZOLES AND QUINOXALINO[2',3'-4,5]IMIDAZO(2,1-B]-BENZOTHIAZOLES [J].

MOHAN, J ;

ANJANEYULU, GSR ;

ARORA, DR .

INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 1987, 26 (02) :183-185

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