Identification of a novel canine norovirus

被引：14

作者：

Bodnar, Livia ^{[1
]}

Lorusso, Eleonora ^{[1
]}

Di Martino, Barbara ^{[2
]}

Catella, Cristiana ^{[1
]}

Lanave, Gianvito ^{[1
]}

Elia, Gabriella ^{[1
]}

Banyai, Krisztian ^{[3
]}

Buonavoglia, Canio ^{[2
]}

Martella, Vito ^{[2
]}

机构：

[1] Univ Aldo Moro Bari, Valenzano, Italy

[2] Univ Teramo, Teramo, TE, Italy

[3] Natl Acad Sci, Budapest, Hungary

来源：

INFECTION GENETICS AND EVOLUTION | 2017年 / 52卷

关键词：

Norovirus; Dogs; Enteritis; Genogroup VI; MOLECULAR CHARACTERIZATION; PARVOVIRUS TYPE-2; CAPSID PROTEIN; NORWALK; INFECTION; DOGS; RECOMBINATION; OUTBREAK; CALICIVIRUS; DIVERSITY;

D O I：

10.1016/j.meegid.2017.04.020

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

By screening a collection of fecal samples from young dogs from different European countries, noroviruses (NoVs) were found in 13/294 (4.4%) animals with signs of enteritis whilst they were not detected in healthy dogs (0/42). An informative portion of the genome (3.4 kb at the 3 ' end) was generated for four NoV strains. In the capsid protein VP1 region, strains 63.15/2015/ITA and FD53/2007/ITA were genetically related to the canine GVI.2 strain C33/Viseu/2007/PRT (97.4-98.6% nt and 903-98.6% aa). Strain FD210/2007/ITA displayed the highest identity to the GVI.1 canine strain Bari/91/2007/ITA (88.0% nt and 95.0% aa). Strain 5010/2009/ITA displayed only 66.6-67.6% nt and 75.5-81.6% aa identities to the GVI.1 canine strains FD210/2007/ITA and Bari/91/2007/ITA and the GVI feline strain M49-1/2012/JPN. Identity to the other canine/feline NoVs strains in the VP1 was lower than 67.6% nt and 62.7% aa. Based on the full-length VP1 amino acid sequence and the criteria proposed for distinction of NoV genotypes, the canine NoV 5010/2009/ITA could represent the prototype of a third GVI genotype, thus providing further evidence for the genetic heterogeneity of NoVs in carnivores. (c) 2017 Elsevier B.V. All rights reserved.

引用

页码：75 / 81

页数：7

共 57 条

[1] The epidemiologic and clinical impartance of norovirus infection [J].