KI catalyzed C-H functionalization of acetone for the synthesis of 2-oxopropyl hetero-aromatic carboxylates

被引：0

作者：

Zhou, Xiao-Yu ^{[1
]}

Chen, Xia ^{[1
]}

Liu, Hai-Long ^{[1
]}

机构：

[1] Liupanshui Normal Univ, Sch Chem & Mat Engn, Liupanshui, Peoples R China

来源：

SYNTHETIC COMMUNICATIONS | 2021年 / 51卷 / 10期

基金：

中国国家自然科学基金;

关键词：

Acetone; C– H functionalization; catalysis; iodide; oxopropyl carboxylates; IODINE; ACCESS;

D O I：

10.1080/00397911.2021.1892762

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

KI catalyzed C-H functionalization of acetone with hetero-aromatic carboxylic acids has been developed. With potassium iodide as catalyst and sodium chlorite as oxidant, cascade reaction including alpha-H electrophilic substitution of acetone and nucleophilic substitution of iodoacetone occur smoothly. 2-Oxopropyl hetero-aromatic carboxylates are obtained with the good to excellent yields.

引用

页码：1556 / 1563

页数：8