KI catalyzed C-H functionalization of acetone for the synthesis of 2-oxopropyl hetero-aromatic carboxylates

被引：0
作者：
Zhou, Xiao-Yu [1 ]
Chen, Xia [1 ]
Liu, Hai-Long [1 ]
机构：
[1] Liupanshui Normal Univ, Sch Chem & Mat Engn, Liupanshui, Peoples R China
来源：
SYNTHETIC COMMUNICATIONS | 2021年 / 51卷 / 10期
基金：
中国国家自然科学基金;
关键词：
Acetone; C– H functionalization; catalysis; iodide; oxopropyl carboxylates; IODINE; ACCESS;
D O I：
10.1080/00397911.2021.1892762
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
KI catalyzed C-H functionalization of acetone with hetero-aromatic carboxylic acids has been developed. With potassium iodide as catalyst and sodium chlorite as oxidant, cascade reaction including alpha-H electrophilic substitution of acetone and nucleophilic substitution of iodoacetone occur smoothly. 2-Oxopropyl hetero-aromatic carboxylates are obtained with the good to excellent yields.
引用
收藏
页码：1556 / 1563
页数：8
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