Synthesis, Characterization, and Antimicrobial Evaluation of Novel 4-Pyrrol-1-yl-5,6,7,8-tetrahydro-pyrido[4′,3′:4,5] Thieno[2,3-d]pyrimidine Derivatives

被引：12

作者：

Parmar, Kokila ^{[1
]}

Suthar, Bharat ^{[1
]}

Suthar, Arun ^{[1
]}

Maheta, Abhay ^{[2
]}

机构：

[1] Hemchandracharya N Gujarat Univ, Dept Chem, Patan 384265, Gujarat, India

[2] Enum Nostrum Remedis, Bombay 400059, Maharashtra, India

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2009年 / 46卷 / 05期

关键词：

CHEMISTRY; EXPLORATION; UREAS;

D O I：

10.1002/jhet.190

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of novel 7-alkyl/aryl sulfonyl-4-pyrrol-1-yl-5,6,7,8-tetrahydro-pyrido[4',3':4,5]thieno[2,3-d] pyrimidine 6 were synthesized for evaluation of their antibacterial and antifungal activity. The structures were determined by IR, NMR, mass spectroscopy, and elemental analysis. They were screened for activities against bacterial and fungal strains.

引用

页码：975 / 979

页数：5

共 31 条

[31] Synthesis and evaluation of aniline headgroups for alkynyl thienopyrimidine dual EGFR/ErbB-2 kinase inhibitors [J].

Waterson, Alex G. ;

Petrov, Kimberly G. ;

Hornberger, Keith R. ;

Hubbard, Robert D. ;

Sammond, Douglas M. ;

Smith, Stephon C. ;

Dickson, Hamilton D. ;

Caferro, Thomas R. ;

Hinkle, Kevin W. ;

Stevens, Kirk L. ;

Dickerson, Scott H. ;

Rusnak, David W. ;

Spehar, Glenn M. ;

Wood, Edgar R. ;

Griffin, Robert J. ;

Uehling, David E. .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2009, 19 (05) :1332-1336

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