Chemistry of N-hydroxyguanidines:: Photo-sensitized oxygenation and reaction with nitric oxide

被引:0
|
作者
Kabasawa, H
Ikeno, M
Suzukawa, M
Higuchi, K
Yanagisawa, K
Seki, H
Tokunaga, T
Ishikawa, T
机构
[1] Chiba Univ, Grad Sch Pharmaceut Sci, Inage Ku, Chiba 2638522, Japan
[2] FIA Instruments Co Ltd, Kita 1140003, Japan
[3] Chiba Univ, Ctr Chem Anal, Inage Ku, Chiba 2638522, Japan
[4] Yamanouchi Pharmaceut Co Ltd, Inst Drug Discovery Res, Mol Chem Anal & Metab Labs, Tsukuba, Ibaraki 3058585, Japan
关键词
D O I
10.1002/1522-2675(200209)85:9<2636::AID-HLCA2636>3.0.CO;2-L
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The chemistry of N-hydroxyguanidines, focusing on photo-sensitized oxygenation and reaction with nitric oxide (NO), was examined. In the former reaction, a urea derivative wits obtained as the main product together with the generation of NO. On the other hand, in the latter case, oxidative nitrosation occurred under aerobic conditions to give a nitrosourea derivative. which wits also obtained from urea by the same treatment.
引用
收藏
页码:2636 / 2643
页数:8
相关论文
共 50 条
  • [31] Mechanism of the Nitric Oxide Dioxygenase Reaction of Mycobacterium tuberculosis Hemoglobin N
    Carabet, Lavinia A.
    Guertin, Michel
    Lague, Patrick
    Lamoureux, Guillaume
    JOURNAL OF PHYSICAL CHEMISTRY B, 2017, 121 (37): : 8706 - 8718
  • [32] Photo-manipulation of vasodilation with a novel photo-controllable nitric oxide releaser based on N-nitrosoaminophenol
    Ieda, Naoya
    Hotta, Yuji
    Kimura, Kazunori
    Miyata, Naoki
    Nakagawa, Hidehiko
    NITRIC OXIDE-BIOLOGY AND CHEMISTRY, 2014, 39 : S48 - S48
  • [34] INSERTION REACTION OF CARBOETHOXYLCARBENE TO N-HEXANE IN THE PRESENCE OF BENZOPHENONE AND THE SENSITIZED PHOTO-OXIDATION OF N-HEXANE
    王葆仁
    郑国琇
    Science in China,SerB, 1984, Ser.B1984 (07) : 665 - 670
  • [35] Reaction of neuronal nitric oxide synthase with the nitric oxide spin-trapping agent, iron complexed with N-dithiocarboxysarcosine
    Yoneyama, H
    Kosaka, H
    Ohnishi, T
    Kawazoe, T
    Mizoguchi, K
    Ichikawa, Y
    EUROPEAN JOURNAL OF BIOCHEMISTRY, 1999, 266 (03): : 771 - 777
  • [36] An ab initio study of the state-specific chemistry of the reaction of iron(I) with nitric oxide
    Thomas, JLC
    Bauschlicher, CW
    Hall, MB
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1996, 212 : 151 - COMP
  • [37] "Click" Reaction in Conjunction with Diazeniumdiolate Chemistry: Developing High-Load Nitric Oxide Donors
    Oladeinde, Oyebola A.
    Hong, Sam Y.
    Holland, Ryan J.
    Maciag, Anna E.
    Keefer, Larry K.
    Saavedra, Joseph E.
    Nandurdikar, Rahul S.
    ORGANIC LETTERS, 2010, 12 (19) : 4256 - 4259
  • [38] CHARACTERISTICS OF THE NITRIC-OXIDE SYNTHASE-CATALYZED CONVERSION OF ARGININE TO N-HYDROXYARGININE, THE FIRST OXYGENATION STEP IN THE ENZYMATIC-SYNTHESIS OF NITRIC-OXIDE
    CAMPOS, KL
    GIOVANELLI, J
    KAUFMAN, S
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (04) : 1721 - 1728
  • [39] CHEMISTRY OF SINGLET OXYGEN .33. NEW PRODUCTS FROM SENSITIZED PHOTO-OXYGENATION OF 1,1-DIPHENYL-2-METHOXY-ETHYLENE
    STEICHEN, DS
    FOOTE, CS
    TETRAHEDRON LETTERS, 1979, (45) : 4363 - 4366
  • [40] The first half reaction of nitric oxide synthase: The conversion of arginine to N-hydroxyarginine.
    Witteveen, CFB
    Giovanelli, J
    Yim, MB
    Kaufman, S
    FASEB JOURNAL, 1997, 11 (09): : A1033 - A1033