General route to a new class of homochiral azetidine-derived 1,2-diamines

被引：18

作者：

Couty, F ^{[1
]}

Evano, G

Prim, D

Marrot, J

机构：

[1] Univ Versailles, CNRS, UMR 8086, Lab SIRCOB, F-78035 Versailles, France

[2] Univ Versailles, CNRS, UMR 8037, Inst Lavoisier, F-78035 Versailles, France

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2004年 / 2004卷 / 18期

关键词：

aminonitriles; azetidines; vicinal diamines;

D O I：

10.1002/ejoc.200400233

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A short access to novel azetidine-derived anti-1,2-diamines starting from easily accessible 2-cyanoazetidines has been developed. A one-pot sequence, including a nucleophilic addition and reduction of the resulting imine, allows for a diastereoselective synthesis of variously substituted diamines. ((C) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004).

引用

页码：3893 / 3897

页数：5

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