20-HYDROXYECDYSONE AND JUVENILE HORMONE INFLUENCE TYROSINE HYDROXYLASE ACTIVITY IN Drosophila FEMALES UNDER NORMAL AND HEAT STRESS CONDITIONS

被引:10
作者
Gruntenko, N. E. [1 ]
Karpova, E. K. [1 ]
Chentsova, N. A. [1 ]
Adonyeva, N. V. [1 ]
Rauschenbach, I. Y. [1 ]
机构
[1] Russian Acad Sci, Siberian Branch, Inst Cytol & Genet, Lavrentieva Ave 10, Novosibirsk 630090, Russia
关键词
Drosophila; tyrosine hydroxylase; 20-hydroxyecdysone juvenile hormone; dopamine; BIOGENIC-AMINE METABOLISM; SILKWORM BOMBYX-MORI; DOPA DECARBOXYLASE; TRIBOLIUM-FREEMANI; OCTOPAMINE LEVELS; TOBACCO HORNWORM; VIRILIS; MELANOGASTER; REPRODUCTION; EXPRESSION;
D O I
10.1002/arch.20337
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The effects of exogenous 20-hydroxyecdysone (20E) and the juvenile hormone (JH) on the activity of the lyrosine hydroxylase (TH), the first, and rate-limiting DA biosynthetic enzyme, has been. studied in young females of wild type D. virilis and D. melanogaster under normal conditions and under heal. stress (38 degrees C). Both 20E feeding of the flies and JH application led to a substantial rise in TH activity. A rise in JH and 20E levels was found not, to Prevent the response of TH to heat. stress, but to change the intensity of its response to the stress exposure. Putative mechanisms of regulation of DA level by 20E and JH in Drosophila females are discussed. (C) 2009 Wiley Periodicals, Inc.
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页码:263 / 272
页数:10
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