Temperature compensation of circadian rhythms: Control of the period in a model for circadian oscillations of the per protein in Drosophila

被引：51
作者：
Leloup, JC
Goldbeter, A
机构：
[1] U. de Chronobiologie Theor., Faculté des Sciences, Campus Plaine, B-1050 Brussels
来源：
CHRONOBIOLOGY INTERNATIONAL | 1997年 / 14卷 / 05期
关键词：
circadian rhythms; temperature compensation; PER protein; model;
D O I：
10.3109/07420529709001472
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
The factors affecting the period are examined in a model for circadian oscillations of the period protein (PER) in Drosophila. The model for the circadian clock is based on multiple phosphorylation of PER and on the negative feedback exerted by PER on the transcription of the period (per) gene. The results are used to address the possible bases of the relative invariance of the period of oscillations with respect to temperature. Such a phenomenon, referred to as temperature compensation, represents one of the most conspicuous properties of circadian rhythms.
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收藏
页码：511 / 520
页数：10
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