Vaccination rate of premature infants at 6 and 24 months of age: A pilot study

There are few data examining the vaccine practices for 0- to 24-month)-old premature infants horn before 33 GW. The aim of the Study was to examine the vaccine coverage in this population according to the French schedule at 6 and 24 months. Results. Eighty-seven infants were included in this regional prospective study. The immunization program began late and was initialized principally with DTPCoqHib) (63%), usually after the 4th month. Fewer than one infant out. of two (45%) had received three (loses by 6 months of age. At 2 years of age, the coverage was 99% at 3 doses and decreased to 83% for 4 (loses. For the MMR vaccine, the average age of administration was after 15 months, and 95% of infants had received one (lose of MMR at 2 years of age. BCG coverage at 2 years of age was 94%, administered oil average at 7 months. Forty-seven percent of the infants had received at least. one dose of hepatitis B vaccine before 2 years of age, but only 31% had received two (loses and a booster at 2 years of age. The adaptation of vaccination practices basically concerns the initial (late of vaccination, but the immunization calendar is not recovered at 2 years of age. This should be taken into account for pertussis disease prevention in these young infants during the first. 6 months (if life, increasing the susceptibility period for this infectious disease. Discussion and conclusion. The vaccine practices do not follow the postnatal chronological age of the Premature baby according to the schedule recommended for full-term infants and vaccination is begun late. Based oil the CSH PF vaccination recommendations, nearly 7 premature infants out of 10 have an incomplete immunization status for DTPCoqHib, hepatitis B, and ROR at 2 years of age. According to the pertussis coverage observed in premature infants, the new recommendations on vaccination of the newborn's care giver and family should be completed before the infant's discharge from the hospital using a new acellular vaccine for adult immunization. The initiation of an immunization program during hospitalization would be beneficial for premature babies still hospitalized after 2 months of age. (C) 2009 Published by Elsevier Masson SAS.