Collagenase for Enzymatic Debridement A Systematic Review

被引：51

作者：

Ramundo, Janet ^{[2
]}

Gray, Mikel ^{[1
]}

机构：

[1] Univ Virginia, Dept Urol, UVA HSC, Charlottesville, VA 22908 USA

[2] Emory Univ, Wound Ost & Continence Nursing Educ Program, Atlanta, GA 30322 USA

来源：

JOURNAL OF WOUND OSTOMY AND CONTINENCE NURSING | 2009年 / 36卷 / 06期

关键词：

DECUBITUS ULCERS; DERMAL ULCERS;

D O I：

10.1097/WON.0b013e3181bfdf83

中图分类号：

R47 [护理学];

学科分类号：

1011 ;

摘要：

Debridement is an essential component of wound bed preparation. Various techniques of debridement are commonly used in clinical practice. This systematic review summarizes and ranks evidence concerning the safety and efficacy of the selective enzymatic debriding agent collagenase. Studies were identified comparing collagenase to inactive (sham) ointment and to alternate techniques for debridement including autolytic and surgical. A preponderance of evidence from this systematic review confirms that collagenase ointment is a safe and effective choice for debridement of cutaneous ulcers and burn wounds.

引用

页码：S4 / S11

页数：8

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