Magnetic drug targeting: biodistribution and dependency on magnetic field strength

被引：209

作者：

Alexiou, C ^{[1
]}

Schmidt, A

Klein, R

Hulin, P

Bergemann, C

Arnold, W

机构：

[1] Univ Erlangen Nurnberg, Dept Otorhinolaryngol Head & Neck Surg, Erlangen, Germany

[2] Tech Univ Munich, Klinikum Rechts Isar, Dept Otorhinolaryngol Head & Neck Surg, D-81675 Munich, Germany

[3] Chemicell, D-10777 Berlin, Germany

来源：

JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS | 2002年 / 252卷 / 1-3期

关键词：

cancer therapy; ferrofluids; magnetic nanoparticles;

D O I：

10.1016/S0304-8853(02)00605-4

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Magnetic drug targeting, a model of locoregional chemotherapy showed encouraging results in treatment of VX2-squamous cell carcinoma in rabbits. In the present study we investigated the biokinetic behavior of Iod([123])-labelled ferrofluids in vivo and showed in vitro that the ferrofluid concentration is dependent on the magnetic field strength. (C) 2002 Elsevier Science B.V. All rights reserved.

引用

页码：363 / 366

页数：4

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