Recurrent Brain Metastasis of Triple Negative Breast Cancer With High Uptake in 68Ga-PSMA-11 PET/CT

被引：9
作者：
Arslan, Esra [1 ]
Ergul, Nurhan [1 ]
Karagoz, Yesim [2 ]
Gedik, Arzu Algun [3 ]
Cermik, Tevfik Fikret [1 ]
机构：
[1] Univ Hlth Sci, Dept Nucl Med, Istanbul Training & Res Hosp, Istanbul, Turkey
[2] Univ Hlth Sci, Dept Radiol, Istanbul Training & Res Hosp, Istanbul, Turkey
[3] Univ Hlth Sci, Dept Pathol, Istanbul Training & Res Hosp, Istanbul, Turkey
来源：
CLINICAL NUCLEAR MEDICINE | 2021年 / 46卷 / 02期
关键词：
triple negative breast cancer (TNBC); F-18-FDG; Ga-68-PSMA-11; PET/CT;
D O I：
10.1097/RLU.0000000000003336
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
Triple negative breast cancer (TNBC) is characterized by poor prognosis and limited response to standard treatments. Although F-18-FDG PET/CT is frequently used in staging and restaging, in some cases, it may be insufficient considering tumor heterogeneity. Prostate-specific membrane antigen (PSMA) has been reported to be overexpressed in many types of cancer due to tumor-associated neovascularization. Ga-68-PSMA-11 PET/CT can be used to demonstrate radionuclide therapy option as well as detection of primary tumor and recurrence in TNBC. We present a 47-year-old woman with TNBC having recurrent brain metastasis with avid PSMA receptor activity versus low FDG uptake.
引用
收藏
页码：E106 / E108
页数：3
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