Two palladium-catalyzed domino reactions from one set of substrates/reagents:: Efficient synthesis of substituted indenes and cis-stilbenoid hydrocarbons from the same internal alkynes and hindered grignard reagents

被引：30

作者：

Dong, Cheng-Guo ^{[1
]}

Yeung, Pik

Hu, Qiao-Sheng

机构：

[1] CUNY Coll Staten Isl, Dept Chem, Staten Isl, NY 10314 USA

[2] CUNY, Grad Ctr, Staten Isl, NY 10314 USA

来源：

ORGANIC LETTERS | 2007年 / 9卷 / 02期

关键词：

D O I：

10.1021/ol062885a

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Two types of domino reactions from the same internal alkynes and hindered Grignard reagents based on carbopalladation, Pd-catalyzed cross-coupling reaction, and a C-H activation strategy are described. The realization of these domino reactions relied on the control of the use of the ligand and the reaction temperature. Our study provides efficient access to useful polysubstituted indenes and cis-substituted stilbenes and may offer a new means of development of tandem/domino reactions in a more efficient way.

引用

页码：363 / 366

页数：4

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