Does the etiology of cardiac amyloidosis determine the myocardial uptake of [18F]-NaF PET/CT?

被引:23
作者
Gagliardi, Christian [1 ]
Tabacchi, Elena [2 ]
Bonfiglioli, Rachele [2 ]
Diodato, Stefania [2 ]
Nanni, Cristina [2 ]
Guidalotti, Pierluigi [2 ]
Lorenzini, Massimiliano [1 ]
Lodi, Filippo [3 ]
Milandri, Agnese [1 ]
Rapezzi, Claudio [1 ]
Fanti, Stefano [2 ]
机构
[1] Univ Bologna, S Orsola Malpighi Hosp, Cardiothoracovasc Dept, DIMES, Bologna, Italy
[2] Univ Bologna, S Orsola Malpighi Hosp, Nucl Med Unit, DIMES, Bologna, Italy
[3] Univ Bologna, S Orsola Malpighi Hosp, Nucl Med Unit, PET Radiopharm, Bologna, Italy
关键词
18F]-NaF PET/CT; cardiac amyloidosis; cardiomyopathy; PET/CT imaging;
D O I
10.1007/s12350-016-0457-8
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Cardiac amyloidosis (CA) leads to variable degrees of myocardial infiltration with a final echocardiographic phenotype of "hypertrophy." Although many non-invasive imaging techniques (MRI, CT, scintigraphy, PET) are useful, the definitive diagnosis is still based on myocardial histology. We explored the possible role of [18F]-NaF PET/CT in the diagnosis of this disease in two cases with wild-type (ATTRwt) or mutant (ATTRm) Ile68Leu transthyretin (TTR)-related CA.
引用
收藏
页码:746 / 749
页数:4
相关论文
共 3 条
[1]   Usefulness and limitations of 99mTc-3,3-diphosphono-1,2-propanodicarboxylic acid scintigraphy in the aetiological diagnosis of amyloidotic cardiomyopathy [J].
Rapezzi, Claudio ;
Quarta, Candida Cristina ;
Guidalotti, Pier Luigi ;
Longhi, Simone ;
Pettinato, Cinzia ;
Leone, Ornella ;
Ferlini, Alessandra ;
Salvi, Fabrizio ;
Gallo, Pamela ;
Gagliardi, Christian ;
Branzi, Angelo .
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2011, 38 (03) :470-478
[2]   Systemic Cardiac Amyloidoses Disease Profiles and Clinical Courses of the 3 Main Types [J].
Rapezzi, Claudio ;
Merlini, Giampaolo ;
Quarta, Candida C. ;
Riva, Letizia ;
Longhi, Simone ;
Leone, Ornella ;
Salvi, Fabrizio ;
Ciliberti, Paolo ;
Pastorelli, Francesca ;
Biagini, Elena ;
Coccolo, Fabio ;
Cooke, Robin M. T. ;
Bacchi-Reggiani, Letizia ;
Sangiorgi, Diego ;
Ferlini, Alessandra ;
Cavo, Michele ;
Zamagni, Elena ;
Fonte, Maria Luisa ;
Palladini, Giovanni ;
Salinaro, Francesco ;
Musca, Francesco ;
Obici, Laura ;
Branzi, Angelo ;
Perlini, Stefano .
CIRCULATION, 2009, 120 (13) :1203-1212
[3]   [18F]-NaF PET/CT imaging in cardiac amyloidosis [J].
Van der Gucht, Axel ;
Galat, Arnault ;
Rosso, Jean ;
Guellich, Aziz ;
Garot, Jerome ;
Bodez, Diane ;
Plante-Bordeneuve, Violaine ;
Hittinger, Luc ;
Dubois-Rande, Jean-Luc ;
Evangelista, Eva ;
Sasanelli, Myriam ;
Chalaye, Julia ;
Meignan, Michel ;
Itti, Emmanuel ;
Damy, Thibaud .
JOURNAL OF NUCLEAR CARDIOLOGY, 2016, 23 (04) :846-849