Mathematical modeling of serine and glycine biosynthesis regulation in Escherichia coli

被引：0

作者：

Turnaev, I. I. ^{[1
]}

Ibragimova, S. S. ^{[1
]}

Usuda, Y. ^{[2
]}

Matsui, K. ^{[2
]}

机构：

[1] SB RAS, Inst Cytol & Genet, Novosibirsk 630090, Russia

[2] Ajinomoto Co Inc, Inst Life Sci, Kawasaki, Kanagawa, Japan

来源：

PROCEEDINGS OF THE FIFTH INTERNATIONAL CONFERENCE ON BIOINFORMATICS OF GENOME REGULATION AND STRUCTURE, VOL 2 | 2006年

关键词：

mathematical modeling; gene network; regulation; serine and glycine biosynthesis; Escherichia coli;

D O I：

暂无

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Motivation: Development of an electronic cell as a resource for use on computers for modeling and analysis of intracellular processes is important to further advancements in systems biology and bioinformatics. To contribute to the progress, it is of importance that mathematical models of cellular metabolic pathway regulation, in particular, regulation of serine and glycine biosynthesis be developed. Results: The gene network for regulation of serine and glycine biosynthesis in E. coli has been reconstructed using the GeneNet technology. Using Hill's generalized functions, mathematical models have been developed for the enzyme reactions. Based on these models, a mathematical model for serine and glycine has been developed.

引用

页码：78 / +

页数：2

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