A Case of Flecainide-Induced Hyponatremia

被引：4

作者：

Ahmed, Mubashir ^{[1
]}

Sra, Jasbir ^{[1
]}

Akhtar, Masood ^{[1
]}

Mortada, M. Eyman ^{[1
]}

机构：

[1] Univ Wisconsin, Sch Med & Public Hlth, Aurora Sinai Electrophysiol Lab, Aurora St luke Med Ctr, Milwaukee, WI USA

来源：

JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY | 2009年 / 20卷 / 10期

关键词：

flecainide; hyponatremia; adverse effects; sodium channels; class 1c antiarrhythmics; atrial tachycardia; SUPRAVENTRICULAR TACHYARRHYTHMIAS; ANTIARRHYTHMIC-DRUGS; SAFETY; EFFICACY; PROPAFENONE; ACETATE;

D O I：

10.1111/j.1540-8167.2009.01450.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Flecainide-Induced Hyponatremia. We present a case of flecainide-induced hyponatremia in a 67-year-old woman who was treated for paroxysmal atrial tachycardia. She developed dizziness after starting flecainide and was found to be hyponatremic with a sodium level of 122 mmol/L (decreased from 136 mmol/L). Work-up failed to reveal other causes of hyponatremia. She was not on diuretics, laxatives, or herbal medications. After discontinuation of flecainide, her symptoms and sodium levels improved. Hyponatremia is a previously unrecognized entity as an adverse effect of flecainide. We will discuss the clinical presentation, lab findings, and a possible explanation for this patient's unusual reaction to flecainide. (J Cardiovasc Electrophysiol, Vol. 20, pp. 1170-1172, October 2009)

引用

页码：1170 / 1172

页数：3

共 14 条

[1] LONG-TERM SAFETY AND EFFICACY OF FLECAINIDE IN THE TREATMENT OF SUPRAVENTRICULAR TACHYARRHYTHMIAS - THE UNITED-STATES EXPERIENCE [J].