Papulonodular mucinosis indicating systemic lupus erythematosus

被引：13

作者：

Shekari, A. Mir ^{[1
]}

Ghiasi, M. ^{[1
]}

Ghasemi, E. ^{[1
]}

Kani, Z. Asadi ^{[2
]}

机构：

[1] Razi Hosp, Dept Dermatol, Iehran, Iran

[2] Danesh Lab, Dept Pathol, Tehran, Iran

来源：

CLINICAL AND EXPERIMENTAL DERMATOLOGY | 2009年 / 34卷 / 08期

关键词：

NODULAR MUCINOSIS; SIGN;

D O I：

10.1111/j.1365-2230.2009.03235.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

We describe an 18-year-old girl with systemic lupus erythematosus (SLE) who had cutaneous papulonodular mucinosis (PNM) as the first sign of SLE. She presented with multiple flesh-coloured papules on the face, abdomen and limbs. Histological examination of a biopsy taken from a papule showed diffuse deposition of mucin throughout the dermis, and direct immunofluorescence of lesional skin showed a dermoepidermal junction band composed of IgG, IgM and C3, consistent with PNM. Investigations showed that that the patient had leucopenia, positive antinuclear and anti-double-stranded DNA antibodies and lupus nephritis. PMN can be an unusual clinical presentation of SLE.

引用

页码：E558 / E560

页数：3

共 10 条

[1]

FOWLER JF, 1984, J RHEUMATOL, V11, P380

[2] AN UNUSUAL PAPULAR ERUPTION ASSOCIATED WITH LUPUS ERYTHEMATOSUS [J].