Movement disorders and cerebrovascular diseases: from pathophysiology to treatment

被引:11
作者
Caproni, Stefano [1 ]
Colosimo, Carlo [1 ]
机构
[1] Azienda Osped Univ Santa Maria, Dipartimento Neurosci, Terni, Italy
关键词
Vascular parkinsonism; hemiballism; hemichorea; basal ganglia; nigrostriatal pathway; levodopa; LEVODOPA-RESPONSIVE PARKINSONISM; PROGRESSIVE SUPRANUCLEAR PALSY; DEEP BRAIN-STIMULATION; RESTLESS LEGS SYNDROME; VASCULAR RISK-FACTORS; WHITE-MATTER LESIONS; BASAL GANGLIA; CLINICAL-FEATURES; ANTIPHOSPHOLIPID SYNDROME; REVERSIBLE PARKINSONISM;
D O I
10.1080/14737175.2017.1267566
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Introduction: Cerebrovascular diseases are one of the most common causes of secondary movement disorders. Hypokinetic or hyperkinetic movement disorders may occur after an ischemic or hemorrhagic stroke, either immediately or thereafter. Such disorders are also known to be caused by diffuse leukoaraiosis, vascular malformations and dural fistulas in the basal ganglia or other brain regions.Area covered: The aim of this review was to describe movement disorders secondary to cerebrovascular diseases, and highlight their pivotal pathophysiological aspects, clinical features, diagnostic criteria and therapeutic options.Expert commentary: Movement disorders secondary to cerebrovascular diseases remain a challenge for neurologists. These conditions share some therapeutic options with idiopathic forms, though tailored treatment may be required in certain cases. Innovative neuroimaging techniques may play a pivotal role in the early diagnosis of vascular movement disorders. Further natural history studies and good-quality clinical trials are warranted to achieve a better management of these complex disorders.
引用
收藏
页码:509 / 519
页数:11
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