1,8-Naphthyridine Derivatives: A Privileged Scaffold for Versatile Biological Activities

被引：14
|
作者：
Ojha, Madhwi [1 ]
Yadav, Divya [1 ]
Kumar, Avinash [2 ]
Dasgupta, Suman [3 ]
Yadav, Rakesh [1 ]
机构：
[1] Banasthali Vidyapith, Dept Pharm, Banasthali 304022, Rajasthan, India
[2] Manipal Acad Higher Educ, Manipal Coll Pharmaceut Sci, Dept Pharmaceut Chem, Manipal 576104, Karnataka, India
[3] Tezpur Univ, Dept Mol Biol & Biotechnol, Sonitpur 784028, Assam, India
来源：
MINI-REVIEWS IN MEDICINAL CHEMISTRY | 2021年 / 21卷 / 05期
关键词：
1,8-Naphthyridine derivatives; nalidixic acid; gemifloxacin; enoxacin; voreloxin; tosufolxacin; TACRINE-DIHYDROPYRIDINE HYBRIDS; ANTIDEPRESSANT-LIKE ACTIVITY; 5-HT3 RECEPTOR ANTAGONISTS; NALIDIXIC-ACID; IN-VITRO; PHARMACOLOGICAL EVALUATION; ANTIINFLAMMATORY ACTIVITY; DNA GYRASE; ANTIMICROBIAL EVALUATION; ANTIBACTERIAL ACTIVITY;
D O I：
10.2174/1389557520666201009162804
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
1, 8- Naphthyridine nucleus belongs to significant nitrogen-containing heterocyclic compounds which has garnered the interest of researchers due to its versatile biological activities. It is known to be used as an antimicrobial, anti-psychotic, anti-depressant, anti-convulsant, anti-Alzheimer's, anti-cancer, analgesic, anti-inflammatory, antioxidant, anti-viral, anti-hypertensive, antimalarial, pesticides, anti-platelets, and CB2 receptor agonist, etc. The present review highlights the framework of biological properties of synthesized 1, 8-naphthyridine derivatives developed by various research groups across the globe.
引用
收藏
页码：576 / 591
页数：16
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