An anti-nuclear antibody-negative patient with systemic lupus erythematosus (SLE) accompanied with anti-ribosomal P antibody (anti-P)

被引：15

作者：

Sugisaki, K ^{[1
]}

Takeda, I ^{[1
]}

Kanno, T ^{[1
]}

Nogai, S ^{[1
]}

Abe, K ^{[1
]}

Sakuma, H ^{[1
]}

Kasukawa, R ^{[1
]}

机构：

[1] Ohta Nishinouchi Hosp, Div Rheumatol, Koriyama, Fukushima 9638558, Japan

来源：

INTERNAL MEDICINE | 2002年 / 41卷 / 11期

关键词：

lupus nephritis; antiphospholipid antibody syndrome; lupus anticoagulant; placental thrombosis;

D O I：

10.2169/internalmedicine.41.1047

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We report a case of an anti-nuclear antibody (ANA)negative patient with systemic lupus erythematosus (SLE) accompanied with anti-phospholipid antibody syndrome (APS) and lupus nephritis (LN). Histological examination of placenta obtained by an artificially-induced abortion revealed multiple thromboses in the placental villi. Histology of biopsied kidney tissue revealed minimal change with deposits of immunoglobulin and complement. Anti-ribosomal P antibodies (anti-P) and lupus anticoagulant (LAC) were positive and anti-double stranded DNA antibody (anti-DNA) showed only a slightly positive titer in her serum. The intensity of proteinuria of the patient was correlated with the anti-P, but not anti-DNA titers.

引用

页码：1047 / 1051

页数：5

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