Reduction in co-trimoxazole resistance in Escherichia coli isolates from urinary tract infections between 1995 and 2005:: a multicenter study in Ankara, Turkey

被引:0
作者
Coplu, Nilay [1 ]
Simsek, Husniye
Gozalan, Aysegul
Hascelik, Gulsen
Ercis, Serpil
Senses, Zeynep
Baysallar, Mehmet
Mumcu, Ipek I.
Balaban, Neriman
Terzioglu, Serdar
Sengul, Ozkan
Esen, Berrin
机构
[1] Refik Saydam Natl Hyg Ctr, Communicable Dis Res Dept, TR-06100 Ankara, Turkey
[2] Hacettepe Univ, Fac Med, Dept Clin Microbiol & Microbiol, TR-06100 Ankara, Turkey
[3] Gulhane Mil Fac Med, Dept Clin Microbiol & Microbiol, Ankara, Turkey
[4] Ankara Numune Govt Hosp, Dept Clin Microbiol & Microbiol, Ankara, Turkey
[5] Dr Sami Ulus Pediat Hosp & Res Ctr, Microbiol Lab, Ankara, Turkey
关键词
drug resistance microbiology; Escherichia coli; co-trimoxazole;
D O I
10.1007/BF03175036
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Co-trimoxazole resistance in Escherichia coli isolates from urinary tract infections (UTI) was assessed in 382 strains from 1995 and 510 strains from 2005. The strains were collected from five microbiology laboratories in Ankara, Turkey. Documentation on patient gender, age and outpatient/inpatient status was collected in 2005, but not in 1995. The resistance percentages were 75.1% in 1995 and 55.5% in 2005. This reduction in resistance percentage was statistically significant, overall in all except two of the participating laboratories. The resistance percentage in 2005 was 61.1% for children (n = 208) and 51.2% for adults (n = 258), 53.7% for females (n = 380) and 60.8% for males (n = 130), and 55.3% for outpatients (n = 400) and 56.4% for inpatients (n = 110). The reduction in resistance is believed to be a consequence of reduced usage. Although decreased, the level of co-trimoxazole resistance remains high, and continued avoidance of its use for empiric treatment of UTI in Turkey appears to be an appropriate strategy.
引用
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页码:379 / 381
页数:3
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