Advances in Stereotactic Body Radiation Therapy for Hepatocellular Carcinoma

被引:90
作者
Murray, Louise J. [1 ,2 ]
Dawson, Laura A. [1 ,2 ]
机构
[1] Univ Toronto, Dept Radiat Oncol, Toronto, ON, Canada
[2] Pnncess Margaret Canc Ctr, Univ Hlth Network, Radiat Med Program, Toronto, ON, Canada
关键词
TRANSCATHETER ARTERIAL CHEMOEMBOLIZATION; INDUCED LIVER-DISEASE; RADIOFREQUENCY ABLATION; RADIOTHERAPY; RESECTION; OUTCOMES; TRANSPLANTATION; SURVIVAL; CYBERKNIFE(R); EXPERIENCE;
D O I
10.1016/j.semradonc.2017.02.002
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Stereotactic Body Radiation Therapy (SBRT) is an emerging effective treatment for hepatocellular carcinoma (HCC) associated with acceptable rates of toxicity in appropriately selected patients. Despite often being reserved for patients unsuitable for other local treatments, prospective and retrospective studies have demonstrated excellent long-term control. SBRT may be used as a stand-alone treatment, or as an adjunct to other HCC therapies. Based on available data, SBRT appears to complement existing local liver therapies. Randomized and nonrandomized comparative studies are required to better determine the optimal role of SBRT in HCC treatment. (C) 2017 Elsevier Inc. All rights reserved.
引用
收藏
页码:247 / 255
页数:9
相关论文
共 58 条
[1]  
Barry AS, 2016, J CLIN ONCOL S1, V34, pS1
[2]   Stereotactic Body Radiation Therapy for Hepatocellular Carcinoma: Prognostic Factors of Local Control, Overall Survival, and Toxicity [J].
Bibault, Jean-Emmanuel ;
Dewas, Sylvain ;
Vautravers-Dewas, Claire ;
Hollebecque, Antoine ;
Jarraya, Hajer ;
Lacornerie, Thomas ;
Lartigau, Eric ;
Mirabel, Xavier .
PLOS ONE, 2013, 8 (10)
[3]   STEREOTAXIC HIGH-DOSE FRACTION RADIATION-THERAPY OF EXTRACRANIAL TUMORS USING AN ACCELERATOR - CLINICAL-EXPERIENCE OF THE FIRST 31 PATIENTS [J].
BLOMGREN, H ;
LAX, I ;
NASLUND, I ;
SVANSTROM, R .
ACTA ONCOLOGICA, 1995, 34 (06) :861-870
[4]   Phase 1 Trial of Sorafenib and Stereotactic Body Radiation Therapy for Hepatocellular Carcinoma [J].
Brade, Anthony M. ;
Ng, Sylvia ;
Brierley, James ;
Kim, John ;
Dinniwell, Robert ;
Ringash, Jolie ;
Wong, Rebecca R. ;
Cho, Charles ;
Knox, Jennifer ;
Dawson, Laura A. .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2016, 94 (03) :580-587
[5]   Improving image-guided target localization through deformable registration [J].
Brock, Kristy K. ;
Hawkins, Maria ;
Eccles, Cynthia ;
Moseley, Joanne L. ;
Moseley, Douglas J. ;
Jaffray, David A. ;
Dawson, Laura A. .
ACTA ONCOLOGICA, 2008, 47 (07) :1279-1285
[6]   Management of Hepatocellular Carcinoma: An Update [J].
Bruix, Jordi ;
Sherman, Morris .
HEPATOLOGY, 2011, 53 (03) :1020-1022
[7]   Sequential Phase I and II Trials of Stereotactic Body Radiotherapy for Locally Advanced Hepatocellular Carcinoma [J].
Bujold, Alexis ;
Massey, Christine A. ;
Kim, John J. ;
Brierley, James ;
Cho, Charles ;
Wong, Rebecca K. S. ;
Dinniwell, Rob E. ;
Kassam, Zahra ;
Ringash, Jolie ;
Cummings, Bernard ;
Sykes, Jenna ;
Sherman, Morris ;
Knox, Jennifer J. ;
Dawson, Laura A. .
JOURNAL OF CLINICAL ONCOLOGY, 2013, 31 (13) :1631-+
[8]   Hepatocellular carcinoma: Consensus, controversies and future directions: A report from the Canadian Association for the Study of the Liver Hepatocellular Carcinoma Meeting [J].
Burak, Kelly Warren ;
Sherman, Morris .
CANADIAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2015, 29 (04) :178-184
[9]   Stereotactic body radiation therapy with or without transarterial chemoembolization for patients with primary hepatocellular carcinoma: preliminary analysis [J].
Choi, Byung Ock ;
Choi, Ihl Bohng ;
Jang, Hong Seok ;
Kang, Young Nam ;
Jang, Ji Sun ;
Bae, Si Hyun ;
Yoon, Seung Kew ;
Chai, Gyu Young ;
Kang, Ki Mun .
BMC CANCER, 2008, 8 (1)
[10]   Outcomes following definitive stereotactic body radiotherapy for patients with Child-Pugh B or C hepatocellular carcinoma [J].
Culleton, Shaelyn ;
Jiang, Haiyan ;
Haddad, Carol R. ;
Kim, John ;
Brierley, Jim ;
Brade, Anthony ;
Ringash, Jolie ;
Dawson, Laura A. .
RADIOTHERAPY AND ONCOLOGY, 2014, 111 (03) :412-417