Autoimmune thyroid disease: Autoimmune gastritis association's possibility

被引：2

作者：

Pita Gutierrez, F. ^{[1
]}

Crespo Marcos, D. ^{[1
]}

Iglesias Fernandez, C. ^{[1
]}

Rodriguez Sanchez, A. ^{[1
]}

Rodriguez Arnao, M. D. ^{[1
]}

机构：

[1] Hosp Infantil Gregorio Maranon, Unidad Metab & Endocrinol Pediat, Madrid, Spain

来源：

ANALES DE PEDIATRIA | 2009年 / 71卷 / 03期

关键词：

Autoimmune thyroid disease; Atrophic chronic gastritis; Autoimmune comorbility; Parietal cell antibodies; Plasmatic hypergastrinemia; ATROPHIC BODY GASTRITIS; PERNICIOUS-ANEMIA; CELL; AUTOANTIBODIES; CHILDREN;

D O I：

10.1016/j.anpedi.2009.05.018

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Introduction: A high prevalence of parietal cell antibodies (PCA) has been reported in children with autoimmune thyroid disease (AITD). The aim of this study was to determine the prevalence of autoimmune gastritis markers among children diagnosed as AITD. Patients and methods: We studied 26 patients with AITD. Basal samples were taken to determine: hemogram, vitamin B12 and folic acid plasmatic levels, gastrin plasmatic levels, and PCA's determination. Other autoimmune disease comorbility were also studied. Results: Free T4 and TSH values were normal, with hormonal substitutive treatment. Hb, MCV, HCM, vitamine B12, folic acid and gastrin were in normal range for all 26 patients. We reported 6 cases diabetes mellitus type 1 and 2 of celiac disease. A single patient was PCA positive. It was a 14-year-old hyperthyroid girl without any other autoimmune disease. Conclusions: AITD in childhood and adolescence is associated with other autoimmune diseases, specially DM1 and CD. PCA becomes an early and sensitive marker to detect autoinmune gastritis. (C) 2009 Asociacion Espanola de Pediatria. Published by Elsevier Espana, S.L. All rights reserved.

引用

页码：240 / 243

页数：4

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