Electrochemical detection of parts-per-billion lead via an electrode-bound DNAzyme assembly

被引：406
作者：
Xiao, Yi
Rowe, Aaron A.
Plaxco, Kevin W. [1 ]
机构：
[1] Univ Calif Santa Barbara, Dept Chem & Biochem, Inst Polymers & Organ Solids, Santa Barbara, CA 93106 USA
[2] Univ Calif Santa Barbara, Dept Phys, Dept Mat, Santa Barbara, CA 93106 USA
[3] Univ Calif Santa Barbara, Program BioMol Sci & Engn, Santa Barbara, CA 93106 USA
来源：
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2007年 / 129卷 / 02期
关键词：
D O I：
10.1021/ja067278x
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
An electrochemical lead sensor is based on lead-dependent changes in the conformational state of a surface-immobilized, methylene-blue modified DNAzyme assembly.
引用
收藏
页码：262 / 263
页数：2
相关论文
共 29 条
[1]   Mutation detection by electrocatalysis at DNA-modified electrodes [J].
Boon, EM ;
Ceres, DM ;
Drummond, TG ;
Hill, MG ;
Barton, JK .
NATURE BIOTECHNOLOGY, 2000, 18 (10) :1096-1100
[2]  
Breaker R R, 1994, Chem Biol, V1, P223, DOI 10.1016/1074-5521(94)90014-0
[3]   Molecular biology - Making catalytic DNAs [J].
Breaker, RR .
SCIENCE, 2000, 290 (5499) :2095-2096
[4]   A lead-dependent DNAzyme with a two-step mechanism [J].
Brown, AK ;
Li, J ;
Pavot, CMB ;
Lu, Y .
BIOCHEMISTRY, 2003, 42 (23) :7152-7161
[5]   In vitro selection of self-cleaving DNAs [J].
Carmi, N ;
Shultz, LA ;
Breaker, RR .
CHEMISTRY & BIOLOGY, 1996, 3 (12) :1039-1046
[6]   Electrochemical detection of lead ions via the covalent attachment of human angiotensin I to mercaptopropionic acid and thioctic acid self-assembled monolayers [J].
Chow, E ;
Hibbert, DB ;
Gooding, JJ .
ANALYTICA CHIMICA ACTA, 2005, 543 (1-2) :167-176
[7]   The Ca2+ ion as a cofactor for a novel RNA-cleaving deoxyribozyme [J].
Faulhammer, D ;
Famulok, M .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1996, 35 (23-24) :2837-2841
[8]   A selective fluorescent sensor for detecting lead in living cells [J].
He, Qiwen ;
Miller, Evan W. ;
Wong, Audrey P. ;
Chang, Christopher J. .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2006, 128 (29) :9316-9317
[9]   Using self-assembly to control the structure of DNA monolayers on gold: A neutron reflectivity study [J].
Levicky, R ;
Herne, TM ;
Tarlov, MJ ;
Satija, SK .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1998, 120 (38) :9787-9792
[10]   A highly sensitive and selective catalytic DNA biosensor for lead ions [J].
Li, J ;
Lu, Y .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2000, 122 (42) :10466-10467
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