PET imaging in patients with brain metastasis-report of the RANO/PET group

被引：149

作者：

Galldiks, Norbert ^{[1
,2
,3
,4
]}

Langen, Karl-Josef ^{[2
,5
]}

Albert, Nathalie L. ^{[6
]}

Chamberlain, Marc ^{[7
,8
]}

Soffietti, Riccardo ^{[9
,10
]}

Kim, Michelle M. ^{[11
]}

Law, Ian ^{[12
]}

Le Rhun, Emilie ^{[13
]}

Chang, Susan ^{[14
]}

Schwarting, Julian ^{[15
,16
]}

Combs, Stephanie E. ^{[17
]}

Preusser, Matthias ^{[18
,19
]}

Forsyth, Peter ^{[20
]}

Pope, Whitney ^{[21
]}

Weller, Michael ^{[22
,23
]}

Tonn, Joerg C. ^{[15
,16
]}

机构：

[1] Univ Hosp Cologne, Dept Neurol, Kerpener St 62, D-50937 Cologne, Germany

[2] Res Ctr Juelich, Inst Neurosci & Med 3 4, Cologne, Germany

[3] Univ Cologne, Ctr Integrated Oncol, Cologne, Germany

[4] Univ Bonn, Ctr Integrated Oncol, Bonn, Germany

[5] Univ Hosp Aachen, Dept Nucl Med, Aachen, Germany

[6] Ludwig Maximilians Univ Munchen, Dept Nucl Med, Munich, Germany

[7] Univ Washington, Fred Hutchinson Canc Res Ctr, Dept Neurol, Seattle, WA 98195 USA

[8] Univ Washington, Fred Hutchinson Canc Res Ctr, Dept Neurol Surg, Seattle, WA 98195 USA

[9] Univ Turin, Dept Neurooncol, Turin, Italy

[10] City Hlth & Sci Hosp, Turin, Italy

[11] Univ Michigan, Dept Radiat Oncol, Ann Arbor, MI 48109 USA

[12] Univ Copenhagen, Rigshosp, Dept Clin Physiol Nucl Med & PET, Copenhagen, Denmark

[13] Univ Hosp Lille, Dept Neurosurg, Lille, France

[14] Univ Calif San Francisco, Dept Neurosurg, San Francisco, CA USA

[15] Ludwig Maximilians Univ Munchen, Dept Neurosurg, Munich, Germany

[16] Partner Site Munich, German Canc Consortium, Munich, Germany

[17] Tech Univ Munich, Dept Radiat Oncol, Munich, Germany

[18] Med Univ Vienna, Dept Med 1, Vienna, Austria

[19] Med Univ Vienna, Ctr Comprehens Canc, CNS Tumours Unit, Vienna, Austria

[20] Univ S Florida, Moffitt Canc Ctr, Tampa, FL USA

[21] Univ Calif Los Angeles, David Geffen Sch Med, Dept Radiol Sci, Los Angeles, CA 90095 USA

[22] Univ Hosp, Dept Neurol, Zurich, Switzerland

[23] Univ Zurich, Zurich, Switzerland

来源：

NEURO-ONCOLOGY | 2019年 / 21卷 / 05期

关键词：

amino acid PET; brain metastases; FDG PET; FET; pseudoprogression; AMINO-ACID PET; POSITRON-EMISSION-TOMOGRAPHY; DYNAMIC F-18-FET PET; LUNG-CANCER PATIENTS; O-(2-F-18-FLUOROETHYL)-L-TYROSINE PET; RESPONSE ASSESSMENT; FDG-PET; RADIATION NECROSIS; SOLID TUMORS; STEREOTACTIC RADIOSURGERY;

D O I：

10.1093/neuonc/noz003

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Brain metastases (BM) from extracranial cancer are associated with significant morbidity and mortality. Effective local treatment options are stereotactic radiotherapy, including radiosurgery or fractionated external beam radiotherapy, and surgical resection. The use of systemic treatment for intracranial disease control also is improving. BM diagnosis, treatment planning, and follow-up is most often based on contrast-enhanced magnetic resonance imaging (MRI). However, anatomic imaging modalities including standard MRI have limitations in accurately characterizing posttherapeutic reactive changes and treatment response. Molecular imaging techniques such as positron emission tomography (PET) characterize specific metabolic and cellular features of metastases, potentially providing clinically relevant information supplementing anatomic MRI. Here, the Response Assessment in Neuro-Oncology working group provides recommendations for the use of PET imaging in the clinical management of patients with BM based on evidence from studies validated by histology and/or clinical outcome.

引用

页码：584 / 595

页数：12

共 111 条

[11] Detection of Brain Metastasis With 68Ga-Labeled PSMA Ligand PET/CT A Novel Radiotracer for Imaging of Prostate Carcinoma [J].