A New and Simple Synthesis of Sulfonyl Ureas from Sulfonamides and N-Alkyl-1,2,4-dithiazolidine-3,5-diones

被引：4
|
作者：
Gessner, Richard K. [1 ]
Chibale, Kelly [1 ,2 ]
机构：
[1] Univ Cape Town, Dept Chem, ZA-7701 Rondebosch, South Africa
[2] Univ Cape Town, Inst Infect Dis & Mol Med, ZA-7701 Rondebosch, South Africa
来源：
SYNLETT | 2009年 / 17期
基金：
新加坡国家研究基金会;
关键词：
sulfonyl ureas; isocyanates; sulfonamides; heterocycles; protecting group; AROMATIC ACYL ISOCYANATES; ONE-POT SYNTHESIS; 1,2,4-DITHIAZOLIDINE-3,5-DIONE; TRIMETHYLSILYLDIAZOMETHANE; DERIVATIVES; FACILE;
D O I：
10.1055/s-0029-1217960
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A new, short, and simple synthetic approach to sulfonyl ureas is reported. The method involves the transformation of readily synthesized N-alkyl-1,2,4-dithiazolidine-3,5-diones by reaction with primary sulfonamides. Sulfonyl ureas were obtained in moderate to high yields.
引用
收藏
页码：2839 / 2843
页数：5
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